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ro5509554

" in TargetMol Product Catalog

Inhibitors & Agonists
1
Inhibitory Antibodies
1

Emactuzumab

T767761448221-67-7

Emactuzumab(RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab has antitumor activity and inhibits activation of colony-stimulating factor 1 receptor (CSF1R) Emactuzumab has a high affinity for CSF-1R with a Ki value of 0.2 nM. Emactuzumab blocks CSF-1R dimerization and can be used to study cancers such as diffuse tenosynovial giant cell tumor (dt-GCT).

c-Fms TAM Receptor

$328

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