s101

S101 is an inhibitor of proliferating T-cells, rescuing mice from superantigen-induced shock.

EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.

KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype.

LAS101057 is a novel orally available and potent and selective A2B receptor antagonist for the study of asthma.

Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule. EDO-S101 is a functional pan-histone-deacetylase inhibitor and is assumed to potentiate the alkylating activity of the compound and/or may help to overcome resistance to other therapeutic agents.

Navoximod phosphate is an indoleamine 2,3-dioxygenase (IDO) inhibitor, immunomodulator and antineoplastic.