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Results for "
sc-144 hydrochloride
" in TargetMol Product Catalog- Inhibitor Products2
SC144 hydrochloride
T41260917497-70-2
SC144 hydrochloride, a first-in-class, orally active, small-molecule gp130 (IL6-beta) inhibitor, demonstrates potent inhibition of gp130 ligand-triggered signaling. By binding to gp130, it initiates gp130 phosphorylation (S782) and deglycosylation, impedes Stat3 phosphorylation and nuclear translocation, and suppresses the expression of downstream target genes. Furthermore, SC144 hydrochloride effectively induces apoptosis in human ovarian cancer cells [1].
- $53
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QTY
SC144
Cited
T6207895158-95-9
SC144 is an orally active small-molecule gp130 inhibitor.
- $39
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Cited Go to page 1
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