sulfo-nhs-lc-biotin sodium

Sulfo-NHS-LC-Biotin sodium is an amine-reactive biotinylation reagent used for antibody labeling.

S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.

Sulfo-NHS-Biotin (Biotin-NHS) is a water-soluble biotinylation reagent used in Biotin-Streptavidin binding reactions. Sulfo-NHS-Biotin is particularly useful for targeting cell surface proteins in Streptavidin-Biotin assays. It can be used for protein detection or immobilization when used in conjunction with streptavidin and Immobilized Streptavidin.

Biotin LC hydrazide (BACH) is a modification reagent of long-chain protein. Biotin LC hydrazide transforms periodate-oxidized glycoproteins and can be used to target glycoproteins and glycans.

Biotin-PEG12-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs.

Biotin-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide (ODN) that antagonizes TLR9, AIM2, and cGAS, serving as a tool for assessing cellular uptake and localization of CpG ODN using biotin detection systems and light microscopy.

6-Maleimidocaproic acid sulfo-NHS serves as an alkyl/ether-based PROTAC linker, facilitating the synthesis of PROTACs.

Biotin-PEG2-NHS ester is a biotinylated polyethylene glycol (PEG)-based linker used in PROTAC synthesis for biotin attachment[1].

TCO-PEG2-Sulfo-NHS ester is a Polyethylene glycol (PEG)-based linker for PROTAC synthesis[1].

Biotin-bis-amido-SS-NHS is an alkyl ether-based PROTAC linker used in the synthesis of PROTACs.

Biotin-LC-LC-NHS, an SMCC cross-linking reagent, acts as a labeling agent for antibodies and small molecules (like Paclitaxel).

Biotin Sodium (Vitamin B7) is a water-soluble B vitamin acting as a coenzyme for five carboxylases critical in human metabolism, including the synthesis of fatty acids, isoleucine, and valine, as well as gluconeogenesis. It is essential for cell growth, fatty acid production, and the metabolism of fats and amino acids [1] [2] [3].

Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, is used to evaluate cellular uptake and localization of CpG ODNs via biotin detection systems and light microscopy.

Biotin-labeled ODN 2395 (sodium), a Class C oligodeoxynucleotide and TLR9 agonist, is used to evaluate cellular uptake and localization of CpG ODN via a biotin detection system integrated with light microscopy.

Sulfo-LC-SPDP is a heterobifunctional crosslinker characterized by its thiol-cleavable and membrane impermeable properties.

Sulfo-SIAB sodium is a non-cleavable monovalent bifunctional linker.

Sulfo-SMPB sodium is a non-cleavable, heterobifunctional chemical cross-linking reagent that combines N-hydroxysuccinimide ester and maleimide groups, enabling the covalent conjugation of molecules possessing (amine) and (sulfhydryl) functionalities.

DBCO-Sulfo-Link-biotin is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Iodoacetyl-LC-Biotin reacts with sulfhydryl groups to form stable thioether linkages.

Biotin-C5-NHS Ester is an alkyl ether-based linker used in PROTAC synthesis [1].

Biotin-PEG4-NHS ester, a biotinylated and PEGylated N-hydroxysuccinimide ester, serves as a linker in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

(+)-Biotin 4-amidobenzoic acid is a substrate of biotinidase, which cleaves biotin amide to give biotin in vivo. Biotin is an essential coenzyme for certain carboxylases and is used to modify histones and regulate gene transcription. Biotinidase has key roles in intestinal absorption of biotin, the transport of biotin in plasma, and in the regulation of histone biotinylation. (+)-Biotin 4-amidobenzoic acid is hydrolyzed by biotinidase to release 4-aminobenzoic acid (PABA), which can be quantified by either fluorescent or colorimetric methods. This approach is used in biotinidase activity assays in newborn screening protocols to evaluate biotinidase deficiency.

Sulfo-SPP sodium is a heterobifunctional, thiol-cleavable, and membrane-impermeable crosslinker.

Biotin-labeled ODN 1826 (sodium), a class B CpG oligodeoxynucleotide (ODN), functions as a TLR9 agonist and enables the evaluation of CpG ODN cellular uptake and localization using biotin detection systems and light microscopy.

Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of CpG ODNs through a biotin detection system with light microscopy.

Biotin-labeled ODN 2216 (sodium) acts as a specific agonist for human TLR9 (toll-like receptor 9), enabling the evaluation of CpG ODN cellular uptake and localization via a biotin detection system coupled with light microscopy.

Biotin-PEG9-NHS Ester is a PEG-based linker for PROTACs, connecting two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-Sulfo-NHS ester sodium is a cleavable linker primarily used in the synthesis of antibody-drug conjugates (ADCs)[1].

1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid. It has been used in PEGylated polyamidoamine-dendrimer-conjugated supported lipid bilayers (SLB) to isolate circulating tumor cells and tumor cell microembolis from patient-derived blood by antibody-coated microfluidics. [1] It has also been used as a component of SLBs to detect protein-ligand binding with ortho-conjugated Texas Red DHPE. [2] In addition, 1,2-dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) has been used in SLBs partitioned into nanowells to create DNA curtains, which can be used as a high-throughput tool for detection of protein-DNA interactions at the single molecule level.[3]

Biotin-PEG24-NHS ester is a PEG-based linker used in PROTACs, facilitating the conjugation of two essential ligands to form PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Bis-SS-C3-sulfo-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Biotin NHS (NHS-Biotin) is an amino reactive biotin reagent used to prepare biotinylated surfaces or polypeptides.

N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker suitable for synthesizing PROTACs [1].

Biotin-PEG6-NHS ester is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Biotin-PEG8-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the [ubiquitin-proteasome system] within cells.

Sulfo-SPDP-C6-NHS sodium is a sodium salt form of a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].

Methyltetrazine-Sulfo-NHS ester (sodium) is an alkyl ether-based PROTAC linker used for PROTAC synthesis [1].

6-O-Sulfo-β-cyclodextrin is a sulfated cyclodextrin.1It has been used for the chiral separation of nadolol racemates by capillary electrophoresis. 1.Wang, F., Dowling, T., Bicker, G., et al.Electrophoretic chiral separation of pharmaceutical compounds with multiple stereogenic centers in charged cyclodextrin mediaJ. Sep. Sci.24(5)378-384(2001)

Sulfo-NHS-Acetate, an alkyl chain-derived PROTAC linker, is utilized for synthesizing PROTACs[1].

Sulfo-SMCC sodium, a widely utilized non-cleavable, hetero-bifunctional crosslinker for antibody-drug conjugates (ADCs), features both N-hydroxysuccinimide (NHS) ester and maleimide groups. These functionalities enable it to specifically react with primary amines and sulfhydryl groups, respectively.

Biotin-labeled ODN 1585 (sodium) effectively induces IFN and TNFα production, and enables assessment of CpG ODN cellular uptake and localization via biotin system detection and light microscopy analysis.

Biotin-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN) and TLR9 agonist, enables the evaluation of cellular uptake and localization of CpG ODNs using a biotin detection system and light microscopy.

Biotin-labeled ODN 2088 (sodium) is a potent inhibitor of TLR3, TLR7, and TLR9, used to evaluate cellular uptake and localization of CpG ODN via a biotin detection system in conjunction with light microscopy.

3-Azidopropionic Acid Sulfo-NHS Ester is a water-soluble compound containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the p

ICG-Sulfo-OSu sodium is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands crucial for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system [in cells].

NHS-SS-biotin is a cleavable linker essential in ADC synthesis, joining cytotoxic drugs to antibodies for precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.

PC-Biotin-PEG4-NHS carbonate, a polyethylene glycol (PEG) derived linker, is utilized in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

The PtdIn phosphates play an important role in the generation and transduction of intracellular signals. PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.