t20

KT203 is a selective and potent structural domain 6 (ABHD6) inhibitor of alpha/beta hydrolytic enzymes with potential antiviral and anti-inflammatory activity for the study of pneumonia.

NPT200-11 is an orally bioavailable and brain penetrating inhibitor of accumulation of alpha-synuclein (ASYN) misfolding and aggregation. NPT200-11 can be used in studies about the underlying pathology of synucleinopathies including Parkinson's disease (PD), dementia with Lewy bodies (DLB) and Multiple Systems Atrophy (MSA).

FT206 is a carboxamide inhibitor of ubiquitin-specific protease[1].

YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.

DT204 is a SCFSkp2 inhibitor which blocks Skp2 binding to Cullin-1 and Commd1, thereby synergistically enhancing BTZ-induced apoptosis and stabilization. DT204 also increases p27 levels.

WL47 is a high-affinity ligand for caveolin-1 (CAV1) with a dissociation constant (Kd) of 23 nM, demonstrating potent disruption of CAV1 oligomers. This compound exhibits selectivity for CAV1, with minimal interaction towards BSA, casein, and HEWL. Notably, WL47's molecular structure is 80% smaller than its T20 parent sequence, rendering it a useful tool for investigating caveolin-1 function [1].

Enfuvirtide acetate salt is a linear synthetic peptide made of 36 amino acids. It has an acetylated N-terminus and a carboxamide C-terminus.

WL47 TFA, a high-affinity cavolin-1 (CAV1) ligand (Kd=23 nM), potently disrupts CAV1 oligomers and exhibits selectivity over BSA, casein, and HEWL. At 80% shorter than the original T20 parent sequence, WL47 TFA is used to investigate caveolin-1 function [1].