tak-220 hydrochloride

TAK-220 hydrochloride is an anti-HIV CCR5 antagonist.

SDZ 220-581 hydrochloride is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).

TAK-220 is a selective and orally bioavailable CCR5 antagonist with IC50 values of 3.5 nM for RANTES binding inhibition and 1.4 nM for MIP-1α binding inhibition to CCR5.

TAK-960 hydrochloride is a potent, selective, orally active inhibitor of polo-like kinase 1 (PLK1) (IC50: 0.8 nM). TAK-960 hydrochloride inhibits the proliferation of a variety of tumour cell lines and significantly treats a variety of tumour xenografts.

TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.

GNE 220 (hydrochloride) is a potent and selective MAP4K4 inhibitor with an IC50 of 7 nM.