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Results for "
tandutinib (mln518) hcl
" in TargetMol Product Catalog- Inhibitors & Agonists3
Tandutinib (MLN518) HCl
T23418
Tandutinib is an effective antagonist for FLT3, platelet-derived growth factor receptor (PDGFR), and c-Kit. Tandutinib potently inhibited the activity of FLT3, PDGFR, and c-Kit (IC50: ~200 nM).
- $78
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Tandutinib
T1667387867-13-2
Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR, and KDR.
- $38
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Tandutinib hydrochloride
T642262438900-70-8
Tandutinib hydrochloride (MLN518 hydrochloride) is a potent, selective FLT3 inhibitor with an IC50 of 0.22 μM and also effectively inhibits c-Kit and PDGFR, with IC50 values of 0.17 μM and 0.20 μM, respectively. This compound is clinically applicable for treating acute myelogenous leukemia (AML) and can cross the blood-brain barrier.
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