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By Target- E1/E2/E3 Enzyme
- NEDD8(1)
- Others(1)
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Results for "
tas-4464 hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists2
TAS4464 hydrochloride
T130901848959-11-4
TAS4464 hydrochloride is a highly potent and selective NEDD8 activating enzyme (NAE) inhibitor(IC50 of 0.955 nM).
Inquiry
TAS-117 hydrochloride
T62907
TAS-117 hydrochloride is a selective, potent, orally active allosteric Akt inhibitor, acting on Akt1 (IC50: 4.8 nM), Akt2 (IC50: 1.6 nM) and Akt3 (IC50: 44 nM). TAS-117 hydrochloride stimulates anti-myeloma activity, enhances lethal endoplasmic reticulum stress induced by proteasome inhibition, and can induce apoptosis and autophagy.
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