thalidomide o peg4 boc

Thalidomide-O-PEG4-Boc is a PEG-based PROTAC linker utilized in PROTAC synthesis [1].

Boc-NH-PEG4-CH2COOH is a cleavable ADC linker utilized in the development of antibody-drug conjugates (ADC)[1].

N-Boc-4-pentyne-1-amine is an alkyl chain-based PROTAC linker compound used in the synthesis of PROTAC MG-277 [1].

Thalidomide-4-OH (E3 ligase Ligand 2) (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used to recruit of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) is a linker to form PROTACs

Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.

Thalidomide-PEG4-Propargyl (Thalidomide-O-PEG4-Propargyl) is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker which can be used in PROTAC technology[1].

Thalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, integrating a Thalidomide-based cereblon ligand with a linker, suitable for PROTAC synthesis.

Thalidomide-O-CH2CONH-CH2COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and linker used in PROTAC technology.

Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is an efficient pegylated PROTAC linker commonly used in the synthesis of chloroanes (HaloPROTACs).

Amino-PEG4-Boc is a PEG-based PROTAC linker suitable for use in PROTAC synthesis[1].

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction [2].

Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) is a synthesized compound that functions as an E3 ligase ligand-linker conjugate.

Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.

Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate incorporating a Thalidomide-based cereblon ligand and a 3-unit PEG linker, used in PROTAC technology.

Hydroxy-PEG4-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC.

Thalidomide-O-amido-PEG2-C2-NH2 TFA (E3 Ligase Ligand-Linker Conjugates 24 TFA) is a synthesized E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a 2-unit PEG linker, utilized in PROTAC technology.

Thalidomide-NH-C4-NH-Boc is a synthesized conjugate used in PROTAC technology, combining a Thalidomide-based cereblon ligand with a linker.

Thalidomide-linker 9 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

Boc-NH-PEG4-CH2CH2NH2 is a cleavable 5-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker. This compound is used in the synthesis of PROTACs.

Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) is a synthesized E3 ligase ligand-linker conjugate.

Thalidomide-O-COOH (Cereblon ligand 3) is a Thalidomide-based Cereblon ligand utilized for recruiting the CRBN protein and can be linked to a protein ligand via a linker to create PROTACs.

Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA) is a synthesized E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker.

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride, incorporating an E3 ligase ligand and a linker, can be used as an immunomodulator for the treatment of cancer.

Boc-NH-O-C1-NHS ester, an alkyl ether-based PROTAC linker, is utilized in PROTAC synthesis.

Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) is a synthesized E3 ligase ligand-linker conjugate incorporating a Thalidomide-based cereblon ligand and a linker used in PROTAC technology.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide amide-alkylC8-amine PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Thalidomide-5-O-C3-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates CRBN protein recruitment and can be conjugated to a protein ligand via a linker to synthesize PROTACs [1].

Propargyl-PEG4-Sulfone-PEG4-Boc is a polyethylene glycol (PEG)-based linker molecule used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

DBCO-C3-PEG4-NH-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG4-NH-Boc, a PEG-based linker for PROTACs, connects two essential ligands, crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG4-amido-PEG4-Boc is a polyethylene glycol (PEG)-based linker utilized for PROTAC synthesis [1].

Thalidomide-O-C8-Boc is a Cereblon ligand derived from Thalidomide, primarily employed in the recruitment of CRBN protein. This ligand can be linked to a protein ligand via a linker to create PROTACs.

Thalidomide-piperazine-Boc, an intermediate used in the synthesis of BCL6 PROTAC, targets the B-cell lymphoma 6 protein.

4-Boc-amino-22-dimethylbutyric acid is an alkyl ether-derived PROTAC linker, suitable for PROTAC synthesis.

Methylamino-PEG4-Boc is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands critical for producing PROTAC molecules, thereby enabling selective protein degradation via the ubiquitin-proteasome system within cells.

3,4-Dibromo-Mal-PEG4-Boc is a polyethylene glycol-based PROTAC linker used for the synthesis of PROTACs[1].

Boc-PEG4-methyl propionate is a polyethylene glycol (PEG)-based linker used in the synthesis of prodrug activation-targeting chimeras (PROTACs).

Boc-aminoxy-PEG4-acid is a PEG-based linker for PROTACs, designed to connect two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl ether-based linker suitable for PROTAC synthesis [1].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Acid-PEG4-C2-Boc, a linker compound based on polyethylene glycol (PEG) and alkyl ether, is utilized in the synthesis of PROteolysis TArgeting Chimeras (PROTACs) for inhibiting the mechanistic Target of Rapamycin (mTOR)[1].

Propargyl-PEG4-Boc is a PEG-based linker for PROTACs, joining two essential ligands to facilitate PROTAC molecule formation. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Dioxoisoindolin-O-PEG-OH (MW 2000) is a polyethylene glycol (PEG)-based linker used in the synthesis of PROTACs (proteolysis targeting chimeras)[1].

Boc-PEG4-sulfonic acid is a PEG-based linker for PROTACs, facilitating the connection between two essential ligands necessary for PROTAC molecule formation, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized conjugate functioning as an E3 ligase ligand-linker, incorporating the cereblon ligand derived from Thalidomide and a linker, and is utilized in the synthesis of PROTAC BET degraders.

Propargyl-PEG4-O-C1-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Thalidomide-O-C8-NH2 hydrochloride is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand derived from Thalidomide, as well as a linker employed in PROTAC technology.

Thalidomide-O-amido-C4-NH2 (Cereblon Ligand-Linker Conjugates 6) is a synthesized compound combining a Thalidomide-based cereblon ligand with a linker, serving as an E3 ligase ligand-linker conjugate for the synthesis of PROTACs[1].

7-O-(Cbz-N-amido-PEG4)-paclitaxel is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.