tos peg1 ch2 boc

Tos-PEG1-CH2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

N-Boc-4-pentyne-1-amine is an alkyl chain-based PROTAC linker compound used in the synthesis of PROTAC MG-277 [1].

Boc-NH-PEG1-OH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs.

Boc-NH-PEG7-Tos (t-Boc-N-Amido-PEG7-Tos) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Hydroxy-PEG4-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC.

Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker employed in PROTAC synthesis [1].

Thalidomide-NH-(CH2)2-NH2 TFA, an alkyl-modified derivative of Thalidomide, functions as a Cereblon ligand to recruit CRBN proteins and serves as a crucial intermediate in the synthesis of CRBN-based PROTAC molecules targeting the SHP2 protein.

Bromo-PEG3-CH2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a polyethylene glycol (PEG)-derived linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Mal-PEG1-Boc is a alkyl ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-Aminooxy-PEG1-azide is a polyethylene glycol (PEG) derived linker compound engineered for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

Azido-PEG4-CH2-Boc, a four-unit cleavable polyethylene glycol (PEG) linker compound, is used in the synthesis of antibody-drug conjugates (ADCs) [1] and PROTACs [2]. Characterized by its azide functional group and PEG backbone, it facilitates drug-antibody conjugation in ADCs and enables PROTAC synthesis using PEG and alkyl ether moieties.

Hydroxy-PEG24-CH2-Boc is a PEG-based linker utilized in PROTACs, facilitating the connection of two essential ligands critical for PROTAC molecule formation, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Boc-Aminooxy-PEG1-C2-NH2 is a polyethylene glycol (PEG)-derived linker compound designed for incorporation into proteolysis targeting chimeras (PROTACs) [1].

N-(PEG1-OH)-N-Boc-PEG2-propargyl is a polyethylene glycol (PEG)-based linker employed in the synthesis of proteolysis targeting chimeras (PROTACs).

Ald-CH2-PEG4-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-N-PEG1-C2-NHS ester, a PEG-based linker, finds utility in PROTAC synthesis[1].

Hydroxy-PEG4-CH2-Boc is a PEG-based linker used in PROTACs, facilitating the conjugation of two critical ligands necessary for PROTAC molecule formation. This linker enables selective protein degradation by exploiting the ubiquitin-proteasome system within cells.

Hydroxy-Amino-bis(PEG1-C2-Boc) is an alkyl ether-based linker utilized in the synthesis of PROTACs [1].

Tos-PEG6-CH2-Boc, a PEG-based linker for PROTACs, connects two essential ligands critical for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

NH2-PEG1-CH2CH2-Boc is a polyethylene glycol (PEG) and alkyl ether-based proteolysis targeting chimeric (PROTAC) linker, frequently used in PROTAC synthesis[1].

CHO-CH2-PEG1-CH2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

1-Boc-azetidine-3-carboxylic acid is a valuable organic compound for life sciences research (catalog number T67359, CAS number 142253-55-2).

Boc-NH-PEG1-Ph-O-CH2COOH is a PROTAC linker used for the EED-targeted PROTAC [1].

Tos-PEG6-C2-Boc, a PEG-based linker for PROTACs, connects two essential ligands critical for forming PROTAC molecules and facilitates selective protein degradation by utilizing the ubiquitin-proteasome system [in cells].

Boc-NH-PEG-amine (MW 3400) is a PEG-based PROTAC linker used in PROTAC synthesis[1].

Amino-PEG24-CH2-Boc, a PEG-based linker for PROTACs, connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

THP-SS-PEG1-Tos is a cleavable 1-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Tos-PEG1-O-CH2COOH (PROTAC Linker 28) is a PEG-based linker used in the synthesis of PROTACs [1].

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate, an ADC linker, is a glutathione-cleavable compound used for attaching monoclonal antibodies (mAb) in antibody-drug conjugates (ADCs), specifically referring to the Alkyl-Chain composition of the linker portion of these molecules [1].

(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is an E3 ligase ligand-linker conjugate designed for targeting the EED protein in PROTAC applications[1].

1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl ether-based PROTAC linker used in the synthesis of PROTACs [1].

(2-Pyridyldithio)-PEG2-Boc is a polyethylene glycol-based PROTAC linker used in the synthesis of PROTACs [1].

Hydroxy-PEG7-CH2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Boc-N-bis(C2-PEG1-azide) is an alkyl ether-based PROTAC linker suitable for synthesizing PROTACs [1].

Bromo-PEG1-C2-Boc is a PEG-based linker for PROTACs, which connects two essential ligands necessary for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-CH2-PEG3-CH2-Boc, a PEG- and Alkyl ether-based PROTAC linker, is utilized for the synthesis of SGK3 kinase PROTAC degrader[1].

Tos-PEG2-NH-Boc is a PEG-based linker for PROTACs that joins two essential ligands to form PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Hydroxy-PEG2-CH2-Boc is a PEG Alkyl ether-based PROTAC linker used in PROTAC synthesis.

Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker used for the synthesis of PROTACs [1].

Tos-PEG4-NH-Boc (PROTAC Linker 7) is a PEG-based linker utilized in the synthesis of PROTACs[1].

Ald-PEG1-C2-Boc is an alkyl-ether-based linker used for synthesizing PROTACs, a class of small molecules inducing targeted protein degradation [1].

Acid-PEG1-C2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized conjugate functioning as an E3 ligase ligand-linker, incorporating the cereblon ligand derived from Thalidomide and a linker, and is utilized in the synthesis of PROTAC BET degraders.

Boc-NHCH2CH2-PEG1-azide is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands crucial for PROTAC molecule formation. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.