tos peg4 t butyl ester

Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker characterized by its PEG composition, crucial in synthesizing various PROTACs, including BI-3663, a selective PTK2 FAK PROTAC. Using cereblon ligands, it targets E3 ligases to degrade PTK2, exhibiting potent inhibitory activity with an IC50 of 18 nM[1].

N3-PEG4-C2-NHS ester is a noncleavable, four-unit polyethylene glycol (PEG) linker essential for the synthesis of antibody-drug conjugates (ADCs).

Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based linker utilized in the synthesis of PROTACs.

DBCO-PEG4-NHS ester is a PEG-based PROTAC linker utilized in PROTAC synthesis[1].

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction [2].

Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a polyethylene glycol (PEG)-based linker crucial for synthesizing proteolysis targeting chimeras (PROTACs)[1].

Diketone-PEG4-PFP ester is a polyethylene glycol (PEG) derivative used as a PROTAC linker in the construction of proteolysis-targeting chimeras (PROTACs) [1].

Tos-PEG4-CH2COOH is a PEG-based linker used in PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

N-Boc-N-bis(PEG4-NHS ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of PROTACs [1].

Biotin-amido-PEG4-PFP ester is a Polyethylene glycol (PEG)-based PROTAC linker used in the synthesis of PROTACs [1].

m-PEG4-Tos, a PEG-based PROTAC linker derived from silybin ethers, finds application in the synthesis of Silymarin[1].

DBCO-PEG4-PFP ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG4-TFP ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules [for selective protein degradation] by leveraging the ubiquitin-proteasome system within cells.

Amino-PEG4-benzyl ester, a PEG- and Alkyl ether-based PROTAC linker, serves as a valuable component for the synthesis of PROTACs[1].

N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a polyethylene glycol (PEG)-based PROTAC linker used in the synthesis of PROTACs[1].

Amino-PEG7-t-butyl ester is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Methyltetrazine-PEG4-SS-NHS ester is a cleavable polyethylene glycol (PEG) linker with four units, frequently used in the synthesis of antibody-drug conjugates (ADCs)[1].

Chloroacetamido-PEG4-NHS ester is a PEG derivative that can be utilized in the development of antibody-agent conjugates (PEG Linkers and derivatives).

N-Mal-N-bis(PEG4-NHS ester) is a polyethylene glycol (PEG)-based bifunctional linker used for synthesizing Proteolysis Targeting Chimeras (PROTACs) [1].

Benzyl-PEG6-t-butyl ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Acid-PEG4-mono-methyl ester, a PEG- and Alkyl ether-based PROTAC linker, can be employed for PROTAC synthesis[1].

NHS-PEG4-(m-PEG12)3-ester is a polyethylene glycol (PEG)-based linker used for PROTAC synthesis [1].

N-Desthiobiotin-N-bis(PEG4-t-butyl ester) is a PEG-based linker compound used in the synthesis of PROTACs, which are bifunctional molecules aimed at targeted protein degradation[1].

m-PEG4-O-NHS ester is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands critical for PROTAC molecule formation and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG4-C2-NHS ester is a non-cleavable, 4-unit PEG linker used in antibody-drug conjugation (ADC) to attach antibodies to drugs.

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group, commonly used in the synthesis of PROTACs[1].

Fmoc-NMe-PEG4-NHS ester, a PEG-derived PROTAC linker, is used in the synthesis of PROTACs [1].

t-Boc-Aminooxy-PEG4-NHS ester is a polyethylene glycol (PEG) derivative that functions as a linker for PROTAC synthesis [1].

Carboxy-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker used in the synthesis of PROTACs, serving as an integral compound [1].

Bis-PEG6-t-butyl ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG4-amino-t-Bu-DADPS-C3-alkyne serves as a PEG-based linker for PROTAC synthesis [1].

Boc-Aminooxy-PEG4-Tos, a PEG-based linker for PROTACs, facilitates the formation of PROTAC molecules by joining two essential ligands and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Mal-PEG4-Lys(t-Boc)-NH-m-PEG24 is a polyethylene glycol (PEG)-based PROTAC linker, ideal for PROTAC synthesis[1].

Tos-PEG4-CH2-Boc is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands critical for the formation of PROTAC molecules, thereby enabling selective protein degradation via the ubiquitin-proteasome system within cells.

endo-BCN-PEG4-NHS ester is a PEG-based linker used in PROTACs, facilitating the connection of two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(m-PEG4)-N'-(4-Hydroxycyclohexyl-1-amido-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker compound primarily used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Boc-PEG4-phosphonic acid ethyl ester is a polyethylene glycol (PEG) derived linker compound used in the synthesis of PROteolysis TArgeting Chimeras (PROTACs) [1].

N-(Tos-PEG4)-N-bis(PEG4-Boc) is a polyethylene glycol (PEG)-based PROTAC linker used in the synthesis of PROTACs[1].

TCO-PEG4-NHS ester is a PROTAC linker bridge in the PEG class, used for synthesizing various PROTAC molecules. As a cleavable and synthetic ADC, it is also utilized in the synthesis of antibody-drug conjugates (ADCs).

Ms-PEG5-t-butyl ester is a PEG-based linker for PROTACs that connects two critical ligands essential for creating PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

m-PEG4-phosphonic acid ethyl ester is a PEGylation-based linker used in the design and synthesis of PROTACs, which are heterobifunctional molecules that facilitate targeted protein degradation[1].

Bromoacetamido-PEG4-NHS ester is a PEGylated N-hydroxysuccinimide ester linker designed for PROTAC synthesis, facilitating the creation of protein-targeted chimeras (PROTACs)[1].

Mal-amido-PEG4-TFP ester, a PEG-based PROTAC linker, finds utility in the synthesis of PROTACs[1].

Propargyl-O-C1-amido-PEG4-C2-NHS ester is a non-cleavable 4-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies with drugs.

Azido-PEG3-S-PEG4-t-butyl ester, a PEG-based PROTAC linker, is used in PROTAC synthesis [1].

Bis-PEG-TFP ester (MW 5000) is a polyethylene glycol (PEG) based linker compound utilized in synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].

Iodoacetyl-PEG4-NHS ester is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N3-PEG4-C2-Pfp ester is a noncleavable, four-unit polyethylene glycol linker used in the fabrication of antibody-drug conjugates (ADCs).

NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker used for synthesizing PROTACs [1].

Azido-PEG4-NHS-ester is a PEG-based linker for PROTACs, joining two essential ligands and facilitating selective protein degradation via the ubiquitin-proteasome system within cells.