traf

TRAF-STOP inhibitor 6877002 (CD40-TRAF6 inhibitor), is a selective inhibitor of CD40-TRAF6 interaction. TRAF-STOP 6877002 reduces leukocyte recruitment, and reduces macrophage activation; reduces macrophage proliferation in atherosclerotic plaques.

TRAF6 peptide TFA, a specific inhibitor of the TRAF6-p62 interaction, significantly inhibits NGF-dependent ubiquitination of TrkA. This peptide demonstrates promising research applications in various neurological disorders, including Alzheimer's disease (AD), Parkinson's, ALS, head trauma, epilepsy, and stroke [1].

TRAF6 peptide, a specific TRAF6-p62 inhibitor, effectively inhibits NGF-dependent TrkA ubiquitination, showcasing strong research potential for neurological conditions including Alzheimer's disease (AD), Parkinson's, ALS, head trauma, epilepsy, and stroke [1].

1,4-Dipierazino-2,3,5,6-tetrafluorobenzene is a tetrafluorobenzene derivative with a unique structure that allows it to be used as a carrier for drugs, which can be released in a controlled manner, enabling its use in the development of targeted drug delivery systems.

SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.

m-(1,1,2,2-Tetrafluoroethoxy)phenyl isocyanate is a bioactive chemical.

Ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)propanoate is a useful organic compound for research related to life sciences. The catalog number is T64869 and the CAS number is 94695-50-8.

Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.

Putraflavone possesses a good antioxidant activity via its DPPH free radical scavenging.

Titanium tetrafluoride is a useful organic compound for research related to life sciences. The catalog number is T35352 and the CAS number is 7783-63-3.

Benzaldehyde, 3-(1,1,2,2-tetrafluoroethoxy)- is a bioactive chemical.

Dalutrafusp alfa (AGEN-1423; GS-1423) is a bifunctional antibody targeting CD73 and TGF-β, components of the immunosuppressive pathway [1].

Lotrafiban is an orally active platelet membrane glycoprotein IIb/IIIa blocker that can be used in the treatment of coronary heart disease and cerebrovascular disease.

Bintrafusp alfa (M 7824), a pioneering bifunctional fusion protein, integrates the extracellular domain of TGF-βRII with a human IgG1 monoclonal antibody that inhibits the programmed cell death ligand. This compound is utilized in cancer research [1].

Polytetrafluoroethylene is a useful organic compound for research related to life sciences. The catalog number is T35377 and the CAS number is 9002-84-0.

BC-1215 is an inhibitor of F-box protein 3 (FBXO3, a ubiquitin E3 ligase component, IC50=0.9 μg mL for IL-1β release).

ALPK1-IN-1 (Compound A001) is a potent inhibitor of alpha-kinase 1 (ALPK1), an intracytoplasmic serine threonine protein kinase involved in the TIFA-dependent pro-inflammatory NF-κB signalling pathway, which activates the innate immune response to bacteria by interacting with TRAF proteins of the forkhead-associated structural domain.