tri(mal-peg-2-amide)-amine

Bis(2-chloroethyl)amine hydrochloride is used as pharmaceutical intermediate.

2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist.

1,2-Diphenylpropan-2-amine is the monohydrochloride metabolite of the (S,R)-isomer of Remacemide.1,2-Diphenylpropan-2-amine has anticonvulsant properties.

2-(5,7-dichloro-1H-indol-3-yl)ethan-1-amine is an indoleamine compound that is structurally similar to serotonin. It is a selective agonist at the 5-HT2A receptor and has potential applications in neuroscience.

3-([2,2':5',2'':5'',2'''-quaterthiophen]-5-yl)propan-1-amine FA is a useful organic compound for research related to life sciences and the catalog number is T67824L.

5-Bromo-2’,3’,5’-tri-O-acetyluridine is a purine nucleoside analog that is being explored to improve Alzheimer’s and Parkinson’s diseases.

Azide-PEG-amine (MW 2000) is a Polyethylene Glycol (PEG) derived linker compound utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

C6-Amide-(PEG)n-CH3 (n=310), an active compound utilized for PEGylation in Egaptivon pegol, is a small molecule crucial for researching platelet dysfunction disorders [1].

Gly-Mal-Gly-Gly-Phe-Gly-amide-methylcyclopropane-Exatecan is a compound utilized in the synthesis of Antibody-Drug Conjugates (ADCs) [1].

(S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].

2-Furoyl-LIGRLO-amide TFA is a peptide that acts as a proteinase-activated receptor-2 (PAR2) agonist, and contains a furoyl group addition at its N-terminal.

Glucocorticoid receptor agonist-2 Ala-Ala-Mal (compound 79) serves as a precursor for synthesizing anti-inflammatory antibody-drug conjugate (ADC) molecules and acts as an active reference for ABBV-3373 [1].

Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide-PEG4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Autocamtide 2, amide is a substrate (100 μM final concentration) for CaMK family assays.Autocamtide-2 Peptide is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), a member of the CAMK Ser/Thr protein kinase

HO-PEG-amine (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

3,7,8-Tri-O-methylellagic acid 2-O-rutinoside is a natural product for research related to life sciences. The catalog number is TN6255 and the CAS number is 56470-18-9.

Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable linker utilized in antibody-drug conjugates (ADCs).

SALMFamide 2, a neuropeptide S2 derived from the starfish Asterias rubens, plays a regulatory role in the eversion of the cardiac stomach in starfish [1].

Amine-PEG-thiol (MW 2000) is a PEG-based PROTAC linker employed in PROTAC synthesis[1].

m-PEG-mal (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DSPE-PEG-Amine (MW 5000) is a polyethylene glycol (PEG)-based PROTAC linker. It serves as an essential PROTAC linker component in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide-PEG5 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Biotin-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative commonly employed as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Amine-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

m-Dioxan-5-amine, 2-(p-chlorophenyl)- is a bioactive chemical.

Amine-PEG-CH2COOH (MW 2000) is a polyethylene glycol (PEG) derivative employed as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Tri(Mal-PEG2-amide)-amine is a polyethylene glycol (PEG)-derived linker commonly employed for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

3 - (5 '- bromo - [2, 2', 5 ', 2 ', 5 ', 2 '- quaterthiophen] - 5 - yl) propan - 1 - amine is a useful organic compound for research in chemistry and life sciences.

Mal-PEG8-amide-Val-Ala-(4-NH2)-Exatecan is a conjugated compound utilized in the synthesis of antibody-drug conjugates (ADCs). This chemical includes a topoisomerase inhibitor derivative attached via a linker, facilitating the connection to a specific ligand unit[1].

Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker enabling the synthesis of PROTACs [1].

m-PEG-mal (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG-Succinimidyl Valerate (MW 20000) is a polyethylene glycol (PEG)-based linker with a molecular weight of 20000. It serves as an essential component in the synthesis of PROTACs, which are proteolysis targeting chimeras.

3-Methylpyridin-2-amine is a useful organic compound for research related to life sciences. The catalog number is T65780 and the CAS number is 1603-40-3.

2',3',5'-Tri-O-acetyl adenosine is a Nucleoside.

6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purine is a 2'-C-Methyl nucleoside; Halo-nucleoside.

3,4-Dibromo-Mal-PEG2-amine is a polyethylene glycol (PEG) derivative and serves as a PEG-based PROTAC linker, facilitating the synthesis of PROTACs[1].

m-Dioxan-5-amine, 2-(p-chlorophenyl)-5-methyl- is a bioactive chemical.

m-Dioxan-5-amine, 2-(3,4-dichlorophenyl)-5-methyl- is a bioactive chemical.

Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH is a chemical linker featuring the TLR4 inhibitor TLR4-IN-C34, known for inhibition of TLR4 in enterocytes and macrophages, thereby diminishing systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis [1].

Nucleoside Derivatives - C-Nucleosides, Pyridine nucleosides

DSPE-PEG(2000)-amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE . It has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.1,2,3DSPE-PEG(2000)-amine has also been used in the synthesis of fluorescein isothiocyanate-loaded mesoporous silica nanoparticles for imaging applications.4It can be conjugated to a variety of functional molecules for improved cellular targeting and uptake of DSPE-PEG(2000)-amine-containing nanoparticles.4,5 1.Sloat, B.R., Sandoval, M.A., Li, D., et al.In vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticlesInt. J. Pharm.409(1-2)278-288(2011) 2.Abd-Rabou, A.A., Bharali, D.J., and Mousa, S.A.Taribavirin and 5-fluorouracil-loaded pegylated-lipid nanoparticle synthesis, p38 docking, and antiproliferative effects on MCF-7 breast cancerPharm. Res.35(4)76(2018) 3.Affram, K., Udofot, O., Singh, M., et al.Smart thermosensitive liposomes for effective solid tumor therapy and in vivo imagingPLoS One12(9):e0815116(2017) 4.Wang, L.-S., Wu, L.-C., Lu, S.-Y., et al.Biofunctionalized phospholipid-capped mesoporous silica nanoshuttles for targeted drug delivery: Improved water suspensibility and decreased nonspecific protein bindingACS Nano4(8)4371-4379(2010) 5.Wen, X., Wang, K., Zhao, Z., et al.Brain-targeted delivery of trans-activating transcriptor-conjugated magnetic PLGA/lipid nanoparticlesPLoS One9(9):e106652(2014)

6-Chloro-2-bromo-9-(2,3,5-tri-O-acetyl)-beta-D-ribofuranosyl-9H-purine is a Nucleoside Derivative - Halo-nucleoside; Scaffold and Template.

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 2 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

2′,3′,5′-Tri-O-acetyl Guanosine is a useful organic compound for research related to life sciences. The catalog number is T67464 and the CAS number is 6979-94-8.

(2',3',5'-Tri-O-acetyl)uridine 5-carboxylic acid is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside.

2-Amino -7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-2,3,5-tri-O-actyl-xylofuranosyl)purine is a useful organic compound for research related to life sciences. The catalog number is TNU1331 and the CAS number is 2389988-52-5.

Mal-C6-amine (TFA) is an alkyl chain-based linker employed in the synthesis of PROTACs[1].

5-Fluoro-2-methoxypyrimidin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T65843 and the CAS number is 1993-63-1.

Amine-PEG-amine (MW 5000) is a polyethylene glycol (PEG) based linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Nucleoside Derivatives - Fluoro-modified nucleosides, 7-Deaza-purine nucleosides