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By Tag By Expression System- HEK293 Cells(2)
By Species- Cynomolgus(1)
- Human(1)
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Results for "
tyro-5
" in TargetMol Product Catalog- Recombinant Protein2
CompareDRT,Nuk,Sek3,TYRO5,EPHT3,HEK5,EphB2,Qek2,PCBC,EPHT3MGC87492,EK5,Cek5,ERK,CAPB
TMPK-00563
EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2α is required for EPHB2 stabilization by hypoxia.
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CompareEC 2.7.10.1,EPHB3,ETK2,EK2,HEK2,AW456895,Sek4,MDK5,Cek10,TYRO6,EC 2.7.10
TMPK-00898
Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC compared to normal mucosa. Hypermethylation of CpG island is contributed to downregulation of EphB3 in CRC. EphB3 expression in tumor cells may be a useful prognostic indicator for patients with CRC.
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