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uk68789

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Dofetilide
T6476115256-11-6
Dofetilide (UK 68789) is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ikr. This antiarrhythmic agent prolongs cardiac action potential duration and effective refractory period due to delayed repolarization without affecting conduction velocity. This results in a normal sinus rhythm. Dofetilide is used in the treatment of atrial fibrillation and flutter.
  • $50
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Dofetilide D4
T110721189700-56-8
Dofetilide D4 (UK 68789 D4), a deuterium-labeled version of Dofetilide, is categorized as a Class III antiarrhythmic medication.
  • $727
35 days
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