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By Target- TAM Receptor
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Results for "
unc569
" in TargetMol Product Catalog- Inhibitors & Agonists3
UNC569
UNC 569
T213021350547-65-7
UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amount of uric acid excreted by gout patients previously classified as under-excretors.
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UNC 569 hydrochloride
UNC 569 hydrochloride (1350547-65-7 Free base)
T21302L
UNC 569 hydrochloride is a reversible and ATP-competitive inhibitor of Mer with an IC50 of 2.9 nM and a Ki of 4.3 nM. UNC 569 hydrochloride inhibits Axl and Tyro3 with IC50s of 37 nM and 48 nM, respectively. UNC 569 hydrochloride can be used in studies about acute lymphoblastic leukemia and atypical teratoid/rhabdoid tumors.
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Lesinurad sodium
Lesinurad,RDEA 594,RDEA-594,RDEA594
T213011151516-14-1
UNC569, the first small-molecule MER inhibitor, inhibits Mer activation and downstream signaling through ERK1/2 and AKTwith. UNC569 shows efficacy against acute lymphoblastic leukemia in vitro and in vivo.
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