unii-06s5u14a4g.

rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b] The EC50 value of pyrazine against TREM2 was ≤ 0.05 μM and the E.max value was > 250 μM.

Methyl 3-[2-[[(4R)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl]methylamino]ethyl]benzoate is a biochemical reagent that can be used to synthesize active compounds.

4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagonist with Ki = 1.0 nM for human CRF-R1.

MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cytochrome c.

Helioxanthin derivative 5-4-2 （Helioxanthin 5-4-2） is an analogue of helioxanthin that shows anti-HBV activity in vitro and can be used to study HBV.

Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM. Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is the R-isomer of Aleglitazar.

4-((benzo[g]quinolin-4-ylamino)methyl)benzenesulfonamide is a chemical agent.

5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative and a metabolite of the antineoplastic agents BIC and DIC. It serves as a condensation agent in the preparation of nucleosides and nucleotides, and when compounded with orotic acid, it is used to treat liver diseases.

4-Amino-5-Chloro-2-Methoxybenzoic Acid (Metoclopramide EP Impurity C) is a Metoclopramide metabolite.

4-Hydroxy-5-methyl-3-furanone (4-Hydroxy-5-methylfuran-3(2H)-one) is a natural product isolated from Eurycotis floridana.

Compound Fr12622 is a useful organic compound for research related to life sciences. The catalog number is Fr12622 and the CAS number is 79047-41-9.

((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate is a pharmaceutical intermediate used in the synthesis of posaconazole with anticancer activity.

ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE used for preparation of pyrimidopyrimidines as protein kinase inhibitors.

(S)-(-)-5-Fluorowillardiine ((S)-5-Fluorowillardiine) is an AMPA receptor-specific agonist.

N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.

ETHYL 2-AMINO-4-METHYL-5-PHENYLTHIOPHENE-3-CARBOXYLATE targets the prostaglandin E2 receptor EP2 subtype (human)

N-(4-bromo-2-chlorophenyl)-5-chloro-2-hydroxybenzamide is a benzamide analog with anti-tumor, anti-inflammatory, anti-bacterial and anti-fungal activities.

2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.

1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl] is an antifibrotic agent.

2-Pyrimidinamine, 4-(5-bromo-1H-indol-3-yl)- (Meridianin C) is a marine derived natural products found in Aplidium meridianum.

Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.

2-amino-4-methyl-1,3-thiazole-5-carbohydrazide (AMTCH) has antitumor activity and inhibits the growth of cancer cells by inducing apoptosis or programmed cell death. It also has antibacterial and fungal activity.

4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid is used as a pharmaceutical intermediate.

4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzoic acid is a synthetic compound with potent antitumor activity, high efficiency and selectivity against tumor cells. However, it has poor solubility in water and is potentially toxic at high concentrations.

5-Amino-4-imidazolecarboxamide is an imidazole derivative.

5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocyclic compound. It inhibits a variety of enzymes such as kinases and phosphodiesterases and has potential therapeutic activity for a variety of diseases.

4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine (5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine) is a marine derived natural products found in Echinodictyum sp.

Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl- is a progesterone receptor antagonist with antiprogestin effects.

4-methylnonan-5-ol is a pheromone of red palm weevils and can be used to capture red palm weevils and reduce their harm to agriculture.

VSV-G Peptide acetate(103425-05-4 free base) is a 11 amino acid peptide derived from the Vesicular Stomatitis viral glycoprotein.

5-TAMRA can produce bright, pH insensitive orange fluorescence (Ex/ Em= 546 / 579nm), and has good photostability

ethyl 1-[(4-cyanobenzyl)oxy]-2-(3-cyanophenyl)-4-methyl-1H-imidazole-5-carboxylate is a platelet aggregation inhibitor.

Antileishmanial agent-2 is a 3-Br-isoxazoline-Based Inhibitors against Plasmodium falciparum (D10 and W2 strains) and Leishmania spp. (L. infantum and L. tropica) Promastigotes with IC50s of 0.035, 0.058, 3.5 and 7.5 μM.

2-(4-methoxyphenyl)-2-oxoethyl 2-hydroxy-5-methylbenzoate is a pro-neurotropic drug used to enhance cognitive function by increasing the synthesis and release of acetylcholine in the brain as well as by inhibiting the breakdown of acetylcholine by acetylcholinesterase.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

5-(5-methyl-1H-1,2,4-triazol-3-yl)-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole can be used in the synthesis of heterocyclic compounds to inhibit HIF pathway activity.

(S)-2-((R)-3-(4-chlorophenyl)-N’-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-methylbutanamide is a cannabinoid receptor antagonist/inverse agonist.

3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).

4-((benzo[g]quinolin-4-yl(methyl)amino)methyl)-N,N-dimethylbenzenesulfonamide is a chemical agent.

Pyrazinecarboxamide, 3,4-dihydro-4-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-3-oxo- is a useful organic compound for research related to life sciences. The catalog number is TNU0422L and the CAS number is 356783-01-2.This compound is unstable in powder form and other related salt forms are recommended.

methyl(Z)-4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-en-2-yl)oxy)benzoate is a useful compound for the synthesis of a variety of organic compounds.

methyl4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-yn-2-yl)oxy)benzoate is a useful compound for the synthesis of a variety of organic compounds.

Cpd.7 of 1326852-06-5 is a useful organic compound for research related to life sciences. The catalog number is T9559 and the CAS number is 2411843-75-7.

S-(5'-Adenosyl)-L-methionine tosylate (SAMe) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases [1]. S-(5'-Adenosyl)-L-methionine tosylate (SAMe) is a stable salt of SAM that is included in nutritional supplements for oral use [2]. S-(5'-Adenosyl)-L-methionine tosylate (SAMe) reportedly ameliorates depression, pain associated with osteoarthritis and fibromyalgia, and liver toxicity [3].

(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid ((S)-3-(4-Hydroxyphenyl)lactic acid) (compound 1) is a metabolite found in the culture medium of Leuconostoc mesenteroides, exhibiting significant DPPH radical-scavenging and antioxidative activities.

L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.

(S)-2-acetamido-4-amino-4-oxobutanoic acid (Nα-Acetyl-L-asparagine), also known as acasn, is an endogenous metabolite.

2-((1R,2R)-2-Formyl-1,3,3-trimethylcyclohexyl)-4-hydroxy-5-isopropylbenzaldehyde is a naturally occurring compound [1].