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unii-2e3s34l69i

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  • Inhibitors & Agonists
    1537
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    199
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    9
    TargetMol | natural
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    5
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    270
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    56
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    TargetMol | composition
2',3'-cGAMP sodium
2'-3'-cyclic GMP-AMP sodium
T10065L2734858-36-5In house
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a second messenger in cellular innate immunity, catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. It binds to STING to form a dimer, inducing the production and expression of interferon-β and other cytokines.
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H-Tyr(3-I)-OH
3-Iodo-L-tyrosine
T556870-78-0
H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones
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L-(R,S)-Tetrahydropalmatine
TETRAHYDROPALMATINE HYDROCHLORIDE
T271410097-84-4
L-(R,S)-Tetrahydropalmatine (Rotundine) is extracted from Corydalis yanhusuo W. T. Wang.
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3-O-Ethyl-L-ascorbic acid
T796686404-04-8
3-O-Ethyl-L-ascorbic acid is a cosmetic tyrosinase inhibitor with whitening ability and is a stabilized vitamin C derivative. It also has antioxidant properties.
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3-Methylbut-2-enoic acid
3,3-Dimethylacrylic Acid,Senecioic acid,3-Methylcrotonic Acid
T5305541-47-9
3-Methylbut-2-enoic acid (Senecioic acid) appears in the urine of patients with 3-Methylcrotonic aciduria, which is a disorder characterized by urine that contains increased amounts of 3-methylcrotonic acid.
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2-(1H-Indol-3-yl)ethan-1-ol
Tryptophol,3-(2-Hydroxyethyl)indole,Indole-3-ethanol
T4876526-55-6
2-(1H-Indol-3-yl)ethan-1-ol (3-(2-Hydroxyethyl)indole) is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation.
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(S)-2-Hydroxy-3-phenylpropanoic acid
L-(−)-3-Phenyllactic acid
T529020312-36-1
(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via lactate dehydrogenase. The D-form is derived from bacterial sources, while the L-form is endogenous. Phenyllactate levels are normally very low in blood or urine, but high levels indicate phenylketonuria (PKU) and hyperphenylalaninemia (HPA). PKU is due to a deficiency of phenylalanine hydroxylase (PAH), causing phenylalanine to convert to phenylpyruvic acid rather than tyrosine.
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3-Amino-2-piperidinone
Cyclo-ornithine
T134951892-22-4
3-Amino-2-piperidinone is a metabolite from all living organisms and can be used as a cyclic ornithine analogue.
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3-Methyl-2-oxobutanoic acid
2-Oxoisovaleric acid,alpha-Ketoisovaleric acid
T5232759-05-7
3-Methyl-2-oxobutanoic acid (2-Oxoisovaleric acid) is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. 3-Methyl-2-oxobutanoic acid is a neurotoxin, an acidogen, and a metabotoxin. A neurotoxin causes damage to nerve cells and nerve tissues. 3-Methyl-2-oxobutanoic acid is a keto-acid, which is a subclass of organic acids. Abnormally high levels of organic acids in the blood (organic acidemia), urine (organic aciduria), the brain, and other tissues lead to general metabolic acidosis.
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S-Adenosyl-L-methionine disulfate tosylate
Ademetionine disulfate tosylate
T675297540-22-2
S-Adenosyl-L-methionine disulfate tosylate (Ademetionine disulfate tosylate) is the disulfate-tosylate mixed salt comprising diastereoisomers of ademetionine ions. Ademetionine exhibits anti-inflammatory properties and has been utilized in the treatment of chronic liver disease.
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2-Acetyl-3-ethylpyrazine
T6704732974-92-8
2-Acetyl-3-ethylpyrazine has antitumor activity.
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7-10 days
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2-Isobutyl-3-methoxypyrazine
3-Isobutyl-2-methoxypyrazine
T6479824683-00-9
2-Isobutyl-3-methoxypyrazine (3-Isobutyl-2-methoxypyrazine) is a RIFM fragrance commonly used in the food and cosmetic industries.
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7-10 days
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(S)-3-Hydroxybutanoic acid
L-β-Hydroxybutyric acid,(S)-β-Hydroxybutanoic acid,L-(+)-3-Hydroxybutyric acid
T139796168-83-8
(S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) is a normal human metabolite that has been found elevated in geriatric patients remitting from depression. (S)-3-Hydroxybutanoic acid is synthesized in the liver from acetyl-CoA in humans, and can be used as an energy source by the brain when blood glucose is low.
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3-Nitro-L-tyrosine
3-Nitrotyrosine
T4890621-44-3
3-Nitro-L-tyrosine (3-Nitrotyrosine) is the major product from the spontaneous reaction of peroxynitrite with tyrosine. Formation of nitrotyrosine can indicate the formation of peroxynitrite by a nitric oxide (NO)-dependent oxidative damage.
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L-Azetidine-2-carboxylic acid
(2S)-azetidine-2-carboxylic acid
TN69282133-34-8
L-Azetidine-2-carboxylic acid ((2S)-azetidine-2-carboxylic acid) is a toxic proline analogue produced by members of the Liliaceae and Agavaciae families.
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Bis(2-methyl-3-furyl)disulfide
Bis(2-methyl-3-furyl)disulphide
T805128588-75-2
Itaconic acid is a precursor for the synthesis of polymers, chemicals, and fuels, and has anti-inflammatory activity.Itaconic acid can be synthesized by fungi. It is also a macrophage-specific metabolite. It mediates crosstalk between macrophage metabolism and peritoneal tumors.
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2-Amino-3-hydroxypyridine
T792316867-03-1
2-Amino-3-hydroxypyridine as a chromogenic reagent for the spectrophotometric determination of osmium.
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(E)-2-Methyl-2-pentenoic acid
trans-2-Methyl-2-pentenoic Acid
T805216957-70-3
(E)-2-Methyl-2-pentenoic acid, characterized by its sweet berry-like aroma and flavor, is widely utilized in food flavoring.
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(E)-2-Butenoic acid
Crotonic acid,alpha-butenoic acid
T5301107-93-7
(E)-2-Butenoic acid (Crotonic acid) is fatty acid formed by the action of fatty acid synthases from acetyl-CoA and malonyl-CoA precursors. Crotonic acid is involved in the fatty acid biosynthesis. Crotonic acid is also found in water extracts from carrot seeds (Daucus carota L.).
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    (E)-3-(4-Methoxyphenyl)acrylic acid
    T41095943-89-5
    (E)-3-(4-Methoxyphenyl)acrylic acid is a small molecule compound isolated from the rhizome of Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. It is a novel α-glucosidase inhibitor with hepatoprotective, antiamnesic, and cognitive enhancement activities, and it can be used to lower blood pressure sugar.
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    7-10 days
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    3-Methyl-2-buten-1-ol
    gamma-dimethylallylalcohol
    T4747556-82-1
    3-Methyl-2-buten-1-ol (gamma-dimethylallylalcohol) is found in blackcurrant, ylang-ylang, hop oils, orange peel oil, and various fruits such as orange, lemon, lime, grape, pineapple, purple passion fruit, and loganberry. Prenol is a flavoring ingredient.
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    L-Ascorbic acid 2-phosphate trisodium
    L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate
    T218566170-10-3
    L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) is utilized in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays.
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    3-Aminopropionitrile fumarate (2:1)
    Di-β-aminopropionitrile fumarate,3-Aminopropionitrile fumarate,β-Aminopropionitrile fumarate,3-Aminopropionitrile fumarate 2:1,Beta-Aminopropionitrile fumarate,β-Ammoniumpropionitrile hemifumarate
    T27692079-89-2
    3-Aminopropionitrile fumarate (2:1) [β-Aminopropionitrile fumarate] is an organic compound and antirheumatic agent utilized in veterinary medicine.
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    2-Methyltetrahydrofuran-3-one
    T80503188-00-9
    2-Methyltetrahydrofuran-3-one, also known as fema 3373 or tetrahydro-2-methyl-3-furanone, belongs to the class of organic compounds known as furanones.
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    Methyl 2-(1H-indol-3-yl)acetate
    Methyl indole-3-acetate,Indole-3-acetic acid, methyl ester
    T47141912-33-0
    Methyl 2-(1H-indol-3-yl)acetate (Methyl indole-3-acetate) is found in apple and isolated from immature seeds of beach pea (Lathyrus maritimus), Vicia amurensis, wild soybean (Glycine soja), lobiya (Vigna catiang var. sinensis), and hyacinth bean (Dolichos lablab).
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    (E)-Oct-2-enoic acid
    trans-2-Octenoic acid,2-Octenoate,2-Octenoic acid
    T52611871-67-6
    (E)-Oct-2-enoic acid (2-Octenoate) is an organic acid produced by hepatic microsomal oxidation of aliphatic aldehydes and is a metabolite naturally present in urine and plasma.
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    2-Hydroxy-3-methoxy chalcone
    TN72267146-86-3
    2-Hydroxy-3-methoxy chalcone has anticancer activity and inhibits colon cancer.
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    1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
    Xanthohumol
    TN5263569-83-5
    1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one (Xanthohumol) , prenylchacone flavonoid, is a natural product with multi-biofunctions purified from Hops Humulus lupulus,is effective against HIV-1 and might serve as an interesting lead compound. It may represent a novel chemotherapeutic agent for HIV-1 infection.
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    L-2-Phosphoglyceric acid
    L-2-Phosphoglyceric acid disodium salt h
    T492923295-92-3
    L-2-Phosphoglyceric acid (L-2-Phosphoglyceric acid disodium salt) is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penultimate step in the conversion of glucose to pyruvate.
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    (2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol
    TN7029
    (2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol is a useful research compound for many research applications, including the fields of chemistry and life sciences, among others.
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    Ellagic acid 3-O-α-L-rhamnopyranoside
    TN72131422265-57-3
    Ellagic acid 3-O-α-L-rhamnopyranoside is a natural product found in the tuberous roots of [Potentilla anserina].
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    (3E)-4-(1H-indol-3-yl)but-3-en-2-one
    4-(1H-indol-3-yl)but-3-en-2-one,(E)-4-(1H-indol-3-yl)but-3-en-2-one
    TN713957598-80-8
    (3E)-4-(1H-indol-3-yl)but-3-en-2-one ((E)-4-(1H-indol-3-yl)but-3-en-2-one) is a marine derived natural products found in Tedania (Tedania) ignis.
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    L-Cysteine S-sulfate
    S-Sulfo-L-cysteine
    T602371637-71-4
    L-Cysteine S-sulfate (S-Sulfo-L-cysteine) is an effective N-methyl-d-aspartate (NMDA) glutamatergic receptors agonist. L-Cysteine S-sulfate is the substrate for cystine lyase [1].
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    6-8 weeks
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    2-Pyrimidinamine, 4-(5-bromo-1H-indol-3-yl)-
    Meridianin C
    TN7180213473-00-8
    2-Pyrimidinamine, 4-(5-bromo-1H-indol-3-yl)- (Meridianin C) is a marine derived natural products found in Aplidium meridianum.
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    2',3',4'-Trimethoxyacetophenone
    TN722213909-73-4
    2',3',4'-Trimethoxyacetophenone is a raw material for the preparation of chalcone compounds with anti-inflammatory activity.
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    2-Propen-1-one, 1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-
    TN712585679-87-4
    2-Propen-1-one, 1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)- can be used in studies about the inhibition against L-phenylalanine ammonia-lyase.
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    (25R)-3β,17α-dihydroxy-5α- spirostan-6-one3-O-α-L- rhamnopyranosyl-(1→2)-β- D-glucopyranoside
    TN7112143051-94-9
    (25R)-3β,17α-dihydroxy-5α- spirostan-6-one3-O-α-L- rhamnopyranosyl-(1→2)-β- D-glucopyranoside is a natural product isolated from the bulbs of Lilium brownii var. viridulum.
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    (+)-6-(2-Hydroxy-3-methoxy-3-methylbutyl
    TN7021L137182-35-5
    (+)-6-(2-Hydroxy-3-methoxy-3-methylbutyl is a structural isomer of Ent-toddalolactone, which belongs to the coumarin group.
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    Kaempferol-3-O-β-D-glucosyl(1-2)rhamnoside
    TN6719142451-65-8
    Kaempferol-3-O-β-D-glucosyl(1-2)rhamnoside is a natural peoduct isolated from Arabian jasmine
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    methyl 2-benzoylamino-3-phenylpropyionate
    TN715974923-17-4
    methyl 2-benzoylamino-3-phenylpropyionate is a natural product found in Aspergillus flavipes.
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    2',3'-cGAMP
    2'-3'-cyclic GMP-AMP
    T100651441190-66-4
    2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a second messenger in cellular innate immunity, catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. It binds to STING to form a dimer, inducing the production and expression of interferon-β and other cytokines.
      7-10 days
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      S-(5'-Adenosyl)-L-methionine tosylate
      SAMe,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt
      T444752248-03-0
      S-(5'-Adenosyl)-L-methionine tosylate (SAMe) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases [1]. S-(5'-Adenosyl)-L-methionine tosylate (SAMe) is a stable salt of SAM that is included in nutritional supplements for oral use [2]. S-(5'-Adenosyl)-L-methionine tosylate (SAMe) reportedly ameliorates depression, pain associated with osteoarthritis and fibromyalgia, and liver toxicity [3].
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      S-Adenosyl-L-methionine
      AdoMet,Ademetionine,SAMe,S-Adenosyl methionine
      T747529908-03-0
      S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.
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      S-allyl-L-cysteine
      S-Allylcysteine
      T277221593-77-1
      S-allyl-L-cysteine (S-Allylcysteine), a natural constituent of fresh garlic, has antioxidant and anticancer properties in animals.
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      3-Hydroxy-2-methylpyridine
      T59011121-25-1
      3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.
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      2'-O-beta-L-galactopyranosylorientin
      2''-O-β-L-Galorientin
      T5713861691-37-4
      2 -O-beta-L-galactopyranosylorientin (2''-O-β-L-Galorientin) is a natual product isaolated from Trollius chinensis Bunge.
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      (S)-2-acetamido-4-amino-4-oxobutanoic acid
      Nα-Acetyl-L-asparagine
      T49334033-40-3
      (S)-2-acetamido-4-amino-4-oxobutanoic acid (Nα-Acetyl-L-asparagine), also known as acasn, is an endogenous metabolite.
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      S-(2-Carboxypropyl)cysteine
      TN71076852-42-2
      S-(2-Carboxypropyl)cysteine is a urinary metabolite of S-(2-Carboxypropyl)glutathione.
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