way 100635 maleate

WAY-100635 Maleate is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM).

WAY-100635 maleate is a selective 5-hydroxytryptamine 1A receptor antagonist with an IC50 value of 0.91 nM and a Ki value of 0.39 nM. It is also a dopamine D4 receptor agonist with pIC50 values of 8.9 and 6.6 for 5-HT1A and α1-adrenergic, respectively.

WAY-100635 is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 of 0.91 nM and Ki of 0.39 nM, exhibiting pIC50 values of 8.9 and 6.6 for 5-HT1A and α1-adrenergic receptors, respectively. Additionally, WAY-100635 acts as a potent agonist of the dopamine D4 receptor [1] [2] [3].