wogonin 7obetadglucuronide methyl ester

5,6-DIAMINOPYRIDINE-3-CARBOXYLIC ACID METHYL ESTER is a useful organic compound for research related to life sciences. The catalog number is T9829 and the CAS number is 104685-76-9.

1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea, a TNF-α agonistic compound, could induce cells to secrete TNF- α.

Methyl 2-(4-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy)phenoxy)propanoate is a selective herbicide, an inhibitor of fatty acid synthesis, and has a systemic effect. After the stem and leaves are treated, it is quickly absorbed by weeds and transmitted to the whole plant, hydrolyzed into acid, and inhibits the growth of root and stem meristems, resulting in death. For soybean, cotton, peanut, rape, nursery, flax, and other broad-leaved crops to control crabgrass, kangaroo, beef tendon grass, barnyard grass, foxtail, chinensis and other annual grass weeds and bermudagrass, imperatae, etc. ineffective against broadleaf grasses and sedges.

7-Methyl-6-mercaptopurine (7-Methyl-6-thiopurine) is an inhibitor of PRPP aminotransferase, inhibits IMP metabolism and prevents purine, DNA and RNA synthesis.

MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cytochrome c.

6-Bromo-1H-indole-3-acetic acid methyl ester (Methyl 6-Bromoindole-3-acetate) is a marine derived natural products found in Pseudosuberites hyalinus.

NG-Nitroarginine methyl ester (ω-Nitroarginine methyl) is a non-selective nitric oxide synthase inhibitor. It has been utilized experimentally to induce hypertension.

Oleoside 11-methyl ester (Methyloleoside) is a natural product.

Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.

Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM. Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is the R-isomer of Aleglitazar.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

Azilsartan Methyl Ester is an angiotensin II receptor antagonist. Azilsartan Methyl Ester inhibits specific binding of [125I]AII (0.2 nM) to bovine adrenal cortex with IC50 value is 0.44uM.

3-(2,6-dichlorophenyl)-1-methyl-7-(methylsulfanyl)-1H,2H,3H,4H-pyrimido[4,5-d][1,3]diazin-4-one is a compound that has been extensively investigated for the treatment of a variety of disorders including tumors, Alzheimer's and Parkinson's diseases, anti-inflammatory drugs, and analgesic agents.

Oseltamivir acid methyl ester hydrochloride is a precursor form of oseltamivir acid. Oseltamivir acid methyl ester is converted to oseltamivir acid converted by carboxylesterase 1 (CES1).

rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine has an EC50 value of ≤ 0.05 μM and an E.max value of > 250 μM for TREM2.

L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) is a lysosomal condensation product that cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes.

CA-074 methyl ester (Cathepsin B Inhibitor IV) is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.

4,5-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV.

2-hydroxy Stearic acid is a hydroxylated fatty acid methyl ester that broadens phase transition in dimyristoylphosphatidylcholine (DMPC) lipid membranes. It has been used in the synthesis of lipid-nucleotide conjugate anti-HIV agents to increase phosphodiester bond cleavage and the amount of liberated intracellular nucleotides.

Acid-PEG5-mono-methyl ester, a PEG-based PROTAC linker, enables the synthesis of PROTACs[1].

Hesperetin-7-methyl ether is a natural prooduct from Citrus maxima.

(±)4(5)-EpDPA methyl ester is a derivative of (±)4(5)-EpDPA which is stable enough to ship and handle routinely. The active free acid can be regenerated from the methyl ester by careful base hydrolysis. (±)4(5)EpDPA is a CYP450 metabolite of DHA which can be further metabolized to the diol metabolite. There are no published reports on the biological activity of (±)4(5)-EpDPA methyl ester at this time.

Amphotericin B methyl ester is the derivative of the antibiotic Amphotericin B. Amphotericin B methyl ester is the cholesterol-binding compound that possesses significant antifungal activity. It disrupts HIV-1 particle production and potently inhibits HIV

Hydroxy-PEG5-C2-methyl ester is a polyethylene glycol (PEG) derived linker compound employed in PROTAC (PROteolysis TArgeting Chimeras) synthesis[1].

Dehydrosoyasaponin I methyl ester, also known as Soyasaponin Be methyl ester, is a saponin compound that is naturally occurring in Trifolium alexandrinum.

URSOLIC ACID METHYL ESTER is a natural product.

3-hydroxy Palmitic acid methyl ester (3-hydroxy PAME) is an esterized long-chain fatty acid involved in quorum sensing in R. solanacearum, a bacteria that causes lethal wilting in plants. 3-hydroxy-PAME (175 nM) increases levels of PhcA-regulated virulence factors, greater than 20-, 30-, and 25-fold for EPS I, EGL, and PME, respectively, in the AW1-83 strain of R. solanacearum.

N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a polyethylene glycol (PEG) derivative used as a PROTAC linker for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable form of PGF2α containing a 16-phenoxy group at the ω-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α. 16-phenoxy tetranor PGF2α methyl ester is a lipophilic analog of 16-phenoxy tetranor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

14-methyl Pentadecanoic acid methyl ester is a methylated fatty acid methyl ester that has been found in S. zeai sea sponges as the fatty acyl component of zeamide, A. indica leaf extract, and C. vulgaris and H. pluvialis microalgae. It is a major component of the vancomycin-induced biofilm produced by vancomycin-resistant S. aureus (VRSA). 14-methyl Pentadecanoic acid methyl ester has been used as a standard for the quantification of 14-methyl pentadecanoic acid in various foods by GC-MS.

3-(beta-D-Glucopyranosyloxy)-2-hydroxybenzoic acid methyl ester is a natural product for research related to life sciences. The catalog number is TN2851 and the CAS number is 53827-68-2.

Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac . It is more soluble than diclofenac acid in isopropylmyristate. Diclofenac methyl ester does not permeate human epidermal membranes in vitro.

7-Aminomethyl-10-methyl-11-fluoro camptothecin, serving as a cytotoxic component of the antibody-drug conjugate (ADC) MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin, is employed in the synthesis of camptothecin ADCs [1].

Glycine, N-[(1,1-dimethylethoxy)carbonyl]thio-L-phenylalanyl-, methyl ester (compound 3b) is a sulfamide-containing polypeptide that can be utilized in the synthesis of peptide-agent coupling compounds [1].

Heteropeucenin 7-methyl ether is a natural product for research related to life sciences. The catalog number is TN6309 and the CAS number is 26213-95-6.

Acid-PEG3-mono-methyl ester, an alkyl/ether-based PROTAC linker, facilitates the synthesis of PROTACs[1].

Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase. It evokes diverse anti-inflammatory effects which may mediate the resolution of inflammation. RvD2 methyl ester is a methyl ester version of the free acid which may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.

Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4 . LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM.

7-O-Methyl morroniside is a natural product from Lonicera morrowii.

(±)5(6)-EpETE methyl ester is a derivative of 5(6)-EpETE which is stable enough to ship and handle routinely.(±) 5(6)-EpETE methyl ester is a chemically less reactive derivative of 5(6)-EpETE. The active free acid can be generated from the methyl ester by careful base hydrolysis. Epoxy eicosatetraenoic acids (EpETEs) are the epoxygenase metabolites of EPA. A number of vicinal diol metabolites of EpETEs have been detected in the plasma of patients on marine oil dietary supplementation, while in subjects on a typical western diet these compounds are generally not detected. The specific biologic activity of 5(6)-EpETE and its methyl ester have not been documented.

Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2α methyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

Methotrexate 1-methyl ester is an impurity of Methotrexate which is a folic acid antagonist. It's used as an antineoplastic and antirheumatic.

Purpurin 18 methyl ester, a derivative of chlorophyll-a, serves as a photosensitizer for photodynamic therapy (PDT), exhibiting the ability to induce cancer cell apoptosis [1].

7-O-Methyl-6-Prenylnaringenin, an active compound, can be isolated from Humulus lupulus [1].

6-(beta-D-glucopyranosyloxy)-Salicylic acid methyl ester is a natural product. The catalog number is TN3155 and the CAS number is 108124-75-0. 6-(beta-D-glucopyranosyloxy)-Salicylic acid methyl ester can be used as a reference standard.

Hydroxy-PEG4-C2-methyl ester is a PEG-based PROTAC linker employed in PROTAC synthesis[1].

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction[2].

Hydroxy-PEG2-C2-methyl ester is a polyethylene glycol (PEG)-based linker commonly employed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

15(S)-HETE methyl ester is a synthetic derivative of 15(S)-HETE , a major arachidonic acid metabolite from the 15-lipoxygenase pathway. Methyl esters of lipids are commonly used in formulations of nutritional supplements.

6-(3-Methyl-2-oxobutyroyl)-7-methoxycoumarin is a natural product for research related to life sciences. The catalog number is TN5877 and the CAS number is 2188162-96-9.