wspc biotin-peg3-dbco

WSPC Biotin-PEG3-DBCO is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the assembly of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

DBCO-S-S-PEG3-biotin is a cleavable reagent for the introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved with reducing agents such as DTT, BME, and TCEP to remove the biotin label. PEG linkers can also be used in the synthesis of PROTACs.

Biotin-PEG-triethoxysilane (MW 2000) is a polyethylene glycol (PEG) derivative functionalized with triethoxysilane and biotin moieties, serving as a PEG-based linker for PROTAC synthesis to facilitate the targeted degradation of proteins of interest.

N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker suitable for synthesizing PROTACs [1].

Biotin-PEG-triethoxysilane (MW 5000) is a PEG-based PROTAC linker used in PROTAC synthesis[1].

DBCO-NHCO-PEG12-biotin is a PEG-based linker for PROTACs that connects two essential ligands critical for forming PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

DBCO-Biotin (Azadibenzocyclooctyne-Biotin conjugate) is a PROTAC linker based on the alkyl chain.

Diazo Biotin-PEG3-DBCO is a cleavable, three-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

DSPE-PEG-Biotin (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.

TAMRA-Azide-PEG-biotin is a PEG-based linker for PROTACs, joining two essential ligands. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Biotin-PEG-Biotin (MW 1000) is a PEG-derived PROTAC linker utilized in PROTAC synthesis [1].

PC DBCO-PEG3-biotin is a trimeric polyethylene glycol (PEG) linker designed for antibody-drug conjugate (ADC) synthesis, incorporating a cleavable moiety with a dibenzocyclooctyne (DBCO) group and a biotin molecule, enabling efficient drug attachment to antibodies for targeted delivery and controlled release of therapeutic agents in ADCs[1].

DBCO-SS-PEG4-Biotin, a cleavable, mid-functional ADC linker with a 4-unit PEG moiety, is used in the synthesis of antibody-drug conjugates (ADCs)[1].

Biotin-PEG-amine (MW 3400) is a polyethylene glycol (PEG)-based linker compound used in the synthesis of PROTACs [1].

Biotin-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative commonly used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

DBCO-NHCO-PEG6-Biotin is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the creation of PROTAC molecules. This linker promotes selective protein degradation by utilizing the ubiquitin-proteasome system [within cells].

Biotin-PEG3-(CH2)3-NH2 TFA salt is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor used as a toxin payload in antibody-drug conjugates, is conjugated via a DBCO-(PEG)3-vc-PAB linker.

Biotin-PEG-triethoxysilane (MW 1000) is a PEG-based PROTAC linker used in the synthesis of PROTACs[1].

Dde Biotin-PEG4-DBCO is a PEG-based linker for PROTACs that connects two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

DBCO-Sulfo-Link-biotin is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

DBCO-NHCO-PEG2-Biotin is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by joining two essential ligands. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

DBCO-NHS ester 3 (Compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (ADC). It is a derivative of Dibenzylcyclooctyne (DBCO) resulting from the activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2].