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By Target- Apoptosis
- Autophagy(1)
- PI3K(1)
- mTOR(1)
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Results for "
wye354
" in TargetMol Product Catalog- Inhibitors & Agonists1
WYE-354
Cited
T67311062169-56-5
WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2 P-AKT(S473) and mTORC1 P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
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