yangonin

Yangonin (Y100550) is a novel CB receptor ligand, it exhibits affinity for the human recombinant CB receptor. Yangonin (Y100550) could be a valuable candidate for the intervention of NF-κB-dependent pathological conditions such as inflammation.

1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydromethysticin and Desmethoxy yangonin involves transcription activation, probably through a PXR-independent or PXR-involved indirect mechanism.

11-Methoxyyangonin (Trimethylhispidin) is a natural kavalactone isolated from Piper methysticum Forst.

4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone is a microbial metabolite of yangonin, a prominent styryl lactone from [Piper methysticum].

5,6-Dihydroyangonin is a useful organic compound for research related to life sciences and the catalog number is T125031.

7,8-Dihydroyangonin is a useful organic compound for research related to life sciences. The catalog number is T125064 and the CAS number is 3155-52-0.