yl 704 a1

Yl 704 A1 is a primary component of macrolide antibiotic YL-704 from Streptomyces platensis subsp. malvinus.

rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b] The EC50 value of pyrazine against TREM2 was ≤ 0.05 μM and the E.max value was > 250 μM.

4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagonist with Ki = 1.0 nM for human CRF-R1.

MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cytochrome c.

2-(1H-Indol-3-yl)ethan-1-ol (3-(2-Hydroxyethyl)indole) is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation.

3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one shows antitumor activity in a human colon cancer cell line and may be used to combat thrombosis.

4-(Imidazol-1-yl)phenol is a potent signal enhancer in horseradish peroxidase (HRP)–luminol chemiluminescence (CL) immunoassays [1].

6-(4-methylpiperazin-1-yl)-4-o-tolylnicotinamide can be used in the synthesis of befetupitant and netupitant.

(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid is a potential SSTR4 agonist.

1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea, a TNF-α agonistic compound, could induce cells to secrete TNF- α.

[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methanamine is a piperazine derivative that is a partial agonist at serotonin and dopamine receptors, making it a candidate for the treatment of psychiatric disorders such as depression and schizophrenia.

1-[10-(pyridin-1-ium-1-yl)decyl]pyridin-1-ium dibromide is the inhibitor of human erythrocyte AChE.

Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagulation factor Xa, and it can be used in the study of thrombophlebitis, atherosclerosis, cerebral embolism, stroke and pulmonary embolism.

((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate is a pharmaceutical intermediate used in the synthesis of posaconazole with anticancer activity.

1-{1H-pyrrolo[2,3-d]pyrimidin-4-yl}piperazine dihydrochloride (1-PPZ-DHC) is a compound used as a molecular structural unit. It is an analog of the natural product piperazine and has a wide range of biological activities, including anti-inflammatory, anti-tumor and antibacterial activities. It has also been studied for the treatment of neurological disorders such as Alzheimer's and Parkinson's.

1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one (Xanthohumol) , prenylchacone flavonoid, is a natural product with multi-biofunctions purified from Hops Humulus lupulus,is effective against HIV-1 and might serve as an interesting lead compound. It may represent a novel chemotherapeutic agent for HIV-1 infection.

(E)-3-(Naphth-1-yl)acrylic acid (3-(1-Naphthyl)acrylic acid) is a biochemical reagent that can be used to synthesize a variety of compounds and participate in many reactions in the body.

N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine is a novel 2,6-naphthyridine identified by high throughput screen (HTS) as a dual protein kinase C/D (PKC/PKD) inhibitor[1].

Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl- is a progesterone receptor antagonist with antiprogestin effects.

(2E,4E)-hexa-2,4-dien-1-yl acetate is an intermediate of the sex pheromone of the codling moth.

6-chloro-1-ethyl-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a compound used as a molecular structural unit for pefloxacin impurities.

2-(5,7-dichloro-1H-indol-3-yl)ethan-1-amine is an indoleamine compound that is structurally similar to serotonin. It is a selective agonist at the 5-HT2A receptor and has potential applications in neuroscience.

1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID targets GRK2.

1-[(5-methylisoxazol-3-yl)methyl]piperazine (Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]-) is a P2Y12 inhibitor.

3-([2,2':5',2'':5'',2'''-quaterthiophen]-5-yl)propan-1-amine FA is a useful organic compound for research related to life sciences and the catalog number is T67824L.

1-(3-chloropyridin-2-yl)piperazine dihydrochloride is a piperazine analog often used as a reagent in organic synthesis, as a ligand in coordination chemistry, and as a drug in pharmaceuticals. It is an inhibitor of DPP4, and DPP4 inhibition has been shown to have beneficial effects in the treatment of certain diseases such as type 2 diabetes and obesity.

1-(1-phenyltetrazol-5-yl)piperazine;hydrochloride (1-(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)piperazine hydrochloride) is a chemical derivative of piperazine that has been used as a starting material for the synthesis of other compounds, such as anti-inflammatory agents. It modulates the activity of enzymes and proteins by binding to their active sites, and has been used in studies of enzyme inhibition and protein structure, as well as in drug metabolism.

N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyrazine-2-carboxamide exhibit an inhibitory effect on bacterial DNA helicases, nucleases, or helicase-nuclease enzyme complexes, such as, for example, one or more enzymes selected from the RecBCD and AddAB families of enzymes.

1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-(pyridin-4-yl)urea is a useful organic compound for research related to life sciences. The catalog number is T67700 and the CAS number is 1144075-47-7.

7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry, exhibiting diverse pharmacological profiles either alone or as a hybrid with other active pharmacophores. It is a potent sirtuin inhibitor, also inhibiting serotonin uptake (IC50 of 50 μM), and demonstrates antimalarial activity on D10 and K1 strains of P. falciparum with IC50 values of 1.18 μM and 0.97 μM, respectively [1].

(S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T65266 and the CAS number is 86069-86-5.

2,5-Dioxopyrrolidin-1-yl ((benzyloxy)carbonyl)-L-alaninate is a useful organic compound for research related to life sciences. The catalog number is T65500 and the CAS number is 3401-36-3.

(S)-N-(1-Amino-5-guanidino-1-oxopentan-2-yl)benzamide hydrochloride, with catalog number T65350 and CAS number 4299-03-0, is a valuable organic compound used in life sciences research.

(2S,4R)-1-((9H-Fluoren-9-yl)methyl) 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate, with catalog number T66076 and CAS number 122350-59-8, is a valuable organic compound for life sciences research.

1-(Piperidin-4-yl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one is a useful organic compound for research related to life sciences and the catalog number is T66378.

1-Octen-3-yl Acetate is a useful organic compound for research related to life sciences. The catalog number is T67145 and the CAS number is 2442-10-6.

(R)-3-(Dimethylamino)-1-(thiophen-2-yl)propan-1-ol is a useful organic compound for research related to life sciences. The catalog number is T66410 and the CAS number is 132335-49-0.

(S)-2-(2-Oxopyrrolidin-1-yl)butanoic acid is a useful organic compound for research related to life sciences. The catalog number is T67078 and the CAS number is 102849-49-0.

1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 2-ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T65490 and the CAS number is 170791-09-0.

Di(adamantan-1-yl)(benzyl)phosphine is a useful organic compound for research related to life sciences and the catalog number is T65005.

(R)-2,5-Dioxopyrrolidin-1-yl 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate is a useful organic compound for research in the life sciences, catalog number T66773, CAS number 3674-18-8.

2-(((6-(Difluoromethoxy)-1H-benzo[d]imidazol-2-yl)sulfonyl)methyl)-3,4-dimethoxypyridine 1-oxide is a useful organic compound for research related to life sciences. The catalog number is T67420 and the CAS number is 953787-55-8.

(2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T66375 and the CAS number is 709031-29-8.

3-(Dimethylamino)-1-(naphthalen-1-yl)propan-1-one hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66115 and the CAS number is 5409-58-5.

1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone is a useful organic compound for research related to life sciences. The catalog number is T67589 and the CAS number is 67914-60-7.

2-(5-(3-(5-Carboxypentyl)-1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-1,1,3-trimethyl-1H-benzo[e]indol-3-ium is a useful organic compound for research related to life sciences and the catalog number is T64625.

1-Chloro-6-(5-(prop-1-ynyl)thiophen-2-yl)hexa-3,5-diyn-2-ol is a natural product from Laggera pterodonta

1-Cyclopropyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66422 and the CAS number is 103460-89-5.