z cyclopentyl ap4

Group III mGlu receptor agonist

α-Cyclopentyl-4-(2-quinolinylmethoxy)benzeneacetic acid was identified as possible dual inhibitors for hLTA4H and hLTC4S enzymes by the computer-aided methodology.

methyl(Z)-4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-en-2-yl)oxy)benzoate is a useful compound for the synthesis of a variety of organic compounds.

(Z)-2-fluoro-1,3-bis(4-methoxyphenyl)prop-2-en-1-one is a screening compound and can be used in new drug development related research.

(E/Z)-4-Hydroxytamoxifen (Afimoxifene) is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer.

AP-III-a4 hydrochloride (ENOblock hydrochloride) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo. IC50 value: 0.576 uM [1]

(Z)-4-Amino-4-oxobut-2-enoic acid (Maleamic acid) is a useful research chemical.

17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).

Compound 7a, (Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate, is a clerodane diterpene [1].

2'',4''-Di-O-(Z-p-coumaroyl)afzelin is a natural product for research related to life sciences. The catalog number is TN2712 and the CAS number is 205534-17-4.

(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one shows strong inhibitory activity on leukotriene biosynthesis in human polymorphonuclear granulocytes, and it is very effective against mycobacteria.

3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol is a useful organic compound for research related to life sciences and the catalog number is T124424.

(Z)-5-Hydroxy-1,7-diphenylhept-4-en-3-one is a natural product for research related to life sciences. The catalog number is TN6362 and the CAS number is 856007-75-5.

3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.

A signal-specific JNK/p38 pathway and TAK 1 inhibitor

4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic acid is an unusual polyunsaturated fatty acid (PUFA) generated during the synthesis of docosahexaenoic acid-d5 . While the physiological properties of this compound are not known, dietary intake of n-3 long-chain PUFAs provides potential health benefits.

3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol is a useful organic compound for research related to life sciences and the catalog number is T125709.

AP-4 is an antagonist of the NMDA glutamate receptor.

Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene is the fluorine analog of Methyl eugenol (ME), the attractant of the oriental fruit fly B. dorsalis.The E-isomer is twice as active as the Z-isomer Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene.

(Z)-2-(2-((tert-Butoxycarbonyl)amino)thiazol-4-yl)pent-2-enoic acid is a useful organic compound for research related to life sciences. The catalog number is T66239 and the CAS number is 86978-24-7.