zearalenone13c18

c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50 = 17 nM) and serves as an anti-inflammatory agent.

Zearalenone-13C18is intended for use as an internal standard for the quantification of zearalenone by GC- or LC-MS. Zearalenone is a mycotoxin that has been found inFusariumand has estrogenic activities.1It binds to human estrogen receptor α (ERα) and ERβ (IC50s = 9 and 5.8 nM, respectively).2Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs.3Zearalenone (1.5-5 mg/kg of diet) induces hyperestrogenism in pigs. It also induces degeneration of meiotic chromatin in oocytes and reduces fertility in pigs when administered at a dose of 200 μg/kg.4Zearalenone has been found as a contaminant in wheat, maize, and barley and livestock feeds.3,4

C-Met-IN-18, an ATP-competitive type-III inhibitor, targets both wild-type (WT) and D1228V mutant c-MET with IC50 values of 0.013 µM and 0.20 µM, respectively. It is utilized in research pertaining to c-MET-driven cancers [1].

PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the remodeling and 'de novo' pathways. It is less potent than PAF C-16 in the induction of platelet aggregation

ent-14,15-Dinor-13-oxolabda-8(17),11-dien-18-oic acid is a natural product of Chloranthus, Chloranthaceae. The catalog number is TN3934 and the CAS number is 875585-30-1. ent-14,15-Dinor-13-oxolabda-8(17),11-dien-18-oic acid can be used as a reference standard.

c-Met-IN-13 is a potent inhibitor of c-Met (IC50: 2.43 nM) that exhibits significant cytotoxicity and anti-proliferative effects against cancer cells in a concentration-dependent and time-dependent manner, demonstrating therapeutic potential against cancer.

15,16-Dihydroxy-8(17),13-labdadien-18-oic acid is a useful organic compound for research related to life sciences and the catalog number is T129903.

13-Oxopodocarp-8(14)-en-18-oic acid is a natural product for research related to life sciences. The catalog number is TN2619 and the CAS number is 63976-69-2.

13(18)-Oleanen-3-ol is a natural product of Cucurbita, Cucurbitaceae. The catalog number is TN1188 and the CAS number is 508-04-3. 13(18)-Oleanen-3-ol can be used as a reference standard.

PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response. It is less potent than PAF C-16 and PAF C-18 in the induction of neutrophil chemotaxis, but is equipotent to PAF C-16 and PAF C-18 in promoting eosinophil migration. PAF C-18:1 activates the PAF receptor and has been used in antibody binding experiments to determine the importance of an acyl linkage at the sn-2 position for recognition at this receptor.

13-Hydroxylabda-8(17),14-dien-18-oic acid is a useful organic compound for research related to life sciences and the catalog number is T124116.

13-Hydroxy-8,11,13-podocarpatrien-18-oic acid is a natural product for research related to life sciences. The catalog number is TN2612 and the CAS number is 61597-83-9.

L-threo-Sphingosine C-18 is a protein kinase C inhibitor.

Zearalenone (F2 toxin) is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in cattle, pigs and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts.

rac Zearalenone-d6 is a deuterated compound of rac Zearalenone.