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By Target- Apoptosis
- Microtubule Associated(1)
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Results for "
zio-301
" in TargetMol Product Catalog- Inhibitors & Agonists1
Indibulin
ZIO 301,D 24851
T15576204205-90-3
Indibulin (D 24851) is a synthetic small molecule with antimitotic and potential antineoplastic activities.Indibulin an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis.
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