TN4635 |
Neoechinulin A
|
51551-29-2
|
98%
|
|
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the ...
|
T13099 |
TC ASK 10
|
1005775-56-3
|
99.71%
|
|
TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1)(IC50 of 14 nM).
|
T67857 |
ASK1-IN-4
|
1427538-26-8
|
99.6%
|
|
ASK1-IN-4 is an ASK1 inhibitor, IC50 = 0.2 μM.
|
T5190 |
GS-444217
|
1262041-49-5
|
99.58%
|
|
GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).
|
T9377 |
ASK1-IN-2
|
2541792-70-3
|
99.36%
|
|
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a...
|
T3101 |
NQDI-1
|
175026-96-7
|
97.19%
|
|
NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).
|
T33514 |
MSC 2032964A
|
1124381-43-6
|
100%
|
|
MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE model...
|
T3350 |
Selonsertib
|
1448428-04-3
|
98%
|
|
Selonsertib (GS-4997) is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and an...
|
T9697 |
ASK1-IN-1
|
2411382-24-4
|
98%
|
|
ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50...
|