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Integrase

Retroviral integrase (IN) is an enzyme produced by a retrovirus (such as HIV) that integrates—forms covalent links between—its DNA (genetic information) into that of the host cell it infects.[citation needed] Retroviral INs are not to be confused with phage integrases (recombinases), such as λ phage integrase, as discussed in site-specific recombination.
Cat No. product name
T2239L Raltegravir Raltegravir is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.
T6589 MK-2048 MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.
T35340 Bictegravir Sodium Bictegravir (GS-9883) Sodium 是一种新型有效的HIV-1 整合酶(HIV-1 integrase)抑制剂,专门针对 IN 链转移活性,IC50 为 7.5 nM。
T2239 Raltegravir potassium Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
TN1671 Ganoderone A Ganoderone A exhibits potent inhibitory activity against herpes simplex virus.
TN4455 Lucialdehyde B Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, an...
Raltegravir
T2239L
Raltegravir is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.
MK-2048
T6589
MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.
Bictegravir Sodium
T35340
Bictegravir (GS-9883) Sodium 是一种新型有效的HIV-1 整合酶(HIV-1 integrase)抑制剂,专门针对 IN 链转移活性,IC50 为 7.5 nM。
Raltegravir potassium
T2239
Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
Ganoderone A
TN1671
Ganoderone A exhibits potent inhibitory activity against herpes simplex virus.
Lucialdehyde B
TN4455
Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, an...