MAO

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.

Cat. No.	Product name	CAS No.	Purity
T15023	CX-157	205187-53-7	98%
T15023	CX-157 is a reversible monoamine oxidase-A (MAO-A) inhibitor (EC50:19.3 ng/mL).
TN3726	Cudraflavone B	19275-49-1	98%
TN3726	Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo...
TN3116	5-Hydroxy-1-methoxyxanthone	27770-13-4	98%
TN3116	5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees o...
TN3918	Echitovenidine	7222-35-7	98%
TN3918	Echitovenidine shows monoamine oxidase inhibitor activity.
TN3024	4'-Demethyleucomin	34818-83-2	98%
TN3024
TN2790	2'-O-Methylperlatolic acid	38968-07-9	98%
TN2790	2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.
TN1099	Dihydroevocarpine	15266-35-0	98%
TN1099	Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...
T16770	Ro 41-1049 hydrochloride	127917-66-2	98%
T16770	Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (Kd: 16.5 and 64.4 nM, respectively).
T5470	LAZABEMIDE	103878-84-8	98%
T5470	LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
TN4137	Glicoricone	161099-37-2	98%
TN4137	Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.
T10079	MAO-IN-1	124991-40-8	98%
T10079	MAO-IN-1 is an inhibitor of monoamine oxidase B (MAO B; IC50: 20 nM).
TN3300	8alpha-Tigloyloxyhirsutinolide 13-O-acetate	83182-58-5	98%
TN3300	8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has ...
TN2553	1-Methyl-2-undecyl-4(1H)-quinolone	59443-02-6	98%
TN2553	1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodi...
TN3294	8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate	67667-71-4	98%
TN3294	8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
T10617	Brofaromine	63638-91-5	98%
T10617	Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
T21652	RN-1 dihydrochloride	1781835-13-9	98%
T21652	RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).
T10146	4-Hydroxyderricin	55912-03-3	98%
T10146	4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-h...
T77578	CHBO4	98991-32-3	98%
T77578	CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the...
T15010	CR4056	1004997-71-0	98%
T15010	CR4056 is a selective inhibitor of MAO-A with IC50 of 202.7 nM and a ligand of I2-imidazoline receptor with IC50 of 596 nM.
TN1470	Cassiaside B2	218155-40-9	98%
TN1470	Cassiaside B2 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A).Cassiaside B2 is an agonist of the 5-HT2C recepto...