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MELK

Maternal embryonic leucine zipper kinase (MELK) is an enzyme that in humans is encoded by the MELK gene. MELK is a serine/threonine kinase belonging to the family of AMPK/Snf1 protein kinases. MELK was first identified present as maternal mRNA in mouse embryos. MELK expression is elevated in a number of cancers and is an active research target for pharmacological inhibition.
Cat. No. Product name CAS No. Purity Chemical Structure
T24152 HTH-01-091 2000209-42-5 98%
HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK...
T11732 JTV-519 hemifumarate 1435938-25-2 98%
JTV-519 hemifumarate,Antiarrhythmic and cardioprotective properties. is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a p...
T35342 MELK-8a Dihydrochloride 98%
T11996 MELK-8a hydrochloride 2096992-20-8 98%
MELK-8a hydrochloride is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK, IC50 = 2 nM). 
T11997 MELK-IN-1 2095596-44-2 98%
MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM).
T12237 NMS-P715 1202055-32-0 98%
NMS-P715 is a selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).
T1759 OTSSP167 1431697-89-0 98%
MELK Inhibitor OTS167 is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.
T21559 OTSSP167 hydrochloride 1431698-10-0 98%
OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).
HTH-01-091
T24152
HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK...
JTV-519 hemifumarate
T11732
JTV-519 hemifumarate,Antiarrhythmic and cardioprotective properties. is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a p...
MELK-8a Dihydrochloride
T35342
MELK-8a hydrochloride
T11996
MELK-8a hydrochloride is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK, IC50 = 2 nM). 
MELK-IN-1
T11997
MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM).
NMS-P715
T12237
NMS-P715 is a selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).
OTSSP167
T1759
MELK Inhibitor OTS167 is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.
OTSSP167 hydrochloride
T21559
OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).