Diosgenin (Nitogenin) is a spirostan found in DIOSCOREA and other plants. It has favorable effects in the improvement of diabetes and regulation of lipid metabolism.

Dioscin (Collettiside III) is a saponin with antitumor activities.

Pseudoprotogracillin is a steroidal saponin extracted from Dioscoreae.

Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek.

8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria, including vancomycin-resistant enterococci.

1. Diosbulbin B exhibits potential hepatotoxicity. 2. Diosbulbin B has potential anti-tumor effects which may be related to influencing the immune system for the first time.

1. Pseudoprotodioscin has moderate cytotoxicity.

Dihydropinosylvinin is an phytoalexin, it shows antifungal activity against Cladosporium cladosporioides, Botryodiplodia theobromae, Aspergillus niger and Penicillium schlerotgenum, it also exhibits strong antibacterial activity against Bacillus cereus, S

Protodioscin (Furostanol I) is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties.

Batatasin I, a natural product from Dioscorea batatas, is a [chemical compound] used for eye research. It is a [useful compound] because it has structural and [chemical properties] ideal for making synthetic antibiotics.

Daucosterol (Sitogluside) has proliferation-enhancing activity, may be involved in the IGF1-AKT pathway. Daucosterol(β-Sitosterol β-D-glucoside) has efficient and inexpensive neuroprotectant effect, to contribute to IGF1-like activity, could be potentially developed as a medicine for ischemic stroke treatment.

Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM).

Protogracillin, a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW), may inhibit platelet aggregation (PAG) and thrombosis, potentially reducing the risk of cardiovascular diseases through its anti-thrombotic action.

Gracillin can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent. Gracillin can be selected as lead compounds for the development of new drugs against I. multifiliis.

Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in human A549 cells is closely associated with Mitochondrial membrane potential, caspase-3, and mitochondrial cytochrome c.

Diosbulbin D shows direct toxic effect on hepatocytes, the mechanism could be associated with oxidative stress.

Diosbulbin G is a natural product of Dioscorea, Dioscoreaceae. The catalog number is TMA0692 and the CAS number is 67567-15-1. Diosbulbin G can be used as a reference standard.

Diosbulbin J is a natural product for research related to life sciences. The catalog number is TN3873 and the CAS number is 1187951-06-9.

Diosbulbin C has hepatotoxicity.

Diosbulbin L is a natural product from Dioscorea bulbifera.