Gordonoside I, a compound isolated from the stem of Chrysanthemum officinale, strongly inhibited the production of nitric oxide in LPS-activated macrophages with an IC50 value of 0.14 μM.
Gordonoside J, a compound isolated from the stem of Chrysanthemum officinale, inhibits LPS-induced nitric oxide production in rat polymorphonuclear leukocytes (PMNS).