sds/T6S2116

(S)-6-methoxychroman-3-carboxylic acid is a synthetic compound with a molecular formula of C11H10O5. It is a member of the chroman family of compounds, which are characterized by a seven-membered ring with one oxygen and one carbon atom.

(S)-GNA-T-phosphoramidite is a nucleoside analog commonly used in the synthesis of other active compounds.

(S)-Methyl 6-(((benzyloxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)hexanoate is a useful organic compound for research related to life sciences. The catalog number is T64462 and the CAS number is 73548-77-3.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylnon-8-enoic acid is a useful organic compound for research related to life sciences. The catalog number is T66542 and the CAS number is 1311933-83-1.

5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4). Mouse liver cytosolic epoxide hydrolase catalyzes the conversion of LTA4 to 5(S),6(R)-DiHETE. It is a weak LTD4 receptor agonist in guinea pig lung membranes. It induces guinea pig ileum contraction with an ED50 value of 1.3 μM.

(2R S)-6-PNG (6-Prenylnaringenin) is a novel natural histone deacetylase inhibitor with anticancer and antitumor activity, and it blocks T-type calcium channels to reduce neuropathic and visceral pain in mice.

Super-chelating agent& MRI contrast agent

6-S-(2-Cyanoethyl)-2’-deoxy-5’-O-DMTr-6-thioguanosine 3’-CED phosphoramidite [catalog number TNU1665] is an essential organic compound for life sciences research.

Azido-PEG3-S-PEG4-t-butyl ester, a PEG-based PROTAC linker, is used in PROTAC synthesis [1].

6-T-GDP (6-Thioguanosine 5'-diphosphate) is a metabolite of thiopurine. It inhibits the activity of Rac1, thereby reducing the transcription of inflammatory factors and the expression of cell adhesion molecules, which ultimately suppresses leukocyte migration and the occurrence of tissue inflammation.

(S)-DMT-glycidol-T is a Nucleoside Derivative - Acyclic nucleoside.

(S)-5-hydroxy-6-methoxy Duloxetine, an active metabolite of the (S)-duloxetine, functions as a serotonin (5-HT) and norepinephrine reuptake inhibitor. Its formation occurs through the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6 via a 5- or 6-hydroxy duloxetine intermediate, followed by a catechol duloxetine intermediate. This compound effectively inhibits the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT) across lipid membranes, with inhibition constants (Kis) of 266, 920, and 2,814 nM, respectively, for human transporters.

5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor. 5(S),6(R)-11-trans DiHETE has been found in rat kidney homogenates and is potentially formed by the epoxide hydrolase pathway in this tissue. The isomerase activity responsible for the conversion of leukotriene B4 (LTB4) to 6-trans LTB4 in rat kidney homogenates has also been implicated in its formation. 5(S),6(R)-11-trans DiHETE is not a substrate for soybean lipoxygenase. The biological activity of 5(S),6(R)-11-trans DiHETE has not been reported.

(S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T66550 and the CAS number is 314771-88-5.

Nucleoside Derivatives - 6-Modified purine nucleosides; Protected nucleosides w/NH2/OH open

The lipoxins are trihydroxy fatty acids containing a 7,9,11,13-conjugated tetraene. Lipoxin A4 (LXA4) was first described as a metabolite of 15-HpETE and/or 15-HETE when added in vitro to isolated human leukocytes. The material obtained in this manner consists of at least four distinct isomers: 5(S), 6(S); 5(S), 6(R); and the 11-trans and 11-cis isomers of each of these. 6(S)-LXA4 is one of the original four metabolites first identified by Serhan, Nicolaou, and Samuelsson. It was considered to be an artifact by these authors because it lacked the potency of the 5(S),6(R) isomer with respect to contraction of isolated guinea pig lung parenchymal strips. It has not been possible to isolate natural LXA4 from humans or other mammals in amounts sufficient for determination of absolute stereochemistry. Most authors refer to LXA4 as the 5(S)

(2′S)-4′-O-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranosylvisamminol, a chromone glycoside, can be isolated from the roots of *Saposhnikovia divaricata* and exhibits weak anti-cancer activity in human cancer cell lines [1].

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-azidohexanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66683 and the CAS number is 159610-89-6.

Dicyclohexylamine (S)-6-(((benzyloxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)hexanoate is a useful organic compound for research related to life sciences. The catalog number is T65798 and the CAS number is 16948-04-2.

(S)-2-Amino-6-(((benzyloxy)carbonyl)amino)hexanoic acid is a useful organic compound for research related to life sciences. The catalog number is T64848 and the CAS number is 1155-64-2.

(S)-2-Amino-3-(6-chloro-1H-indol-3-yl)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T64941 and the CAS number is 33468-35-8.

(S)-9-(2,3-Dihydroxypropyl)-2-amino-6-chloropurine is a Nucleoside Derivative - Acyclic nucleoside.

(S,S)-2,3-Bis(t-butylmethylphosphino)quinoxaline is a useful organic compound for research related to life sciences and the catalog number is T64832.

6-S-Methyl-6-thio-inosine is a Nucleoside Derivative - 6-Modified purine nucleoside; Thio-nucleoside.

Heterocyclic Compounds - Triazines; Intermediates and Building Blocks - Electrophiles

(S)-6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(((benzyloxy)carbonyl)amino)hexanoic acid is a useful organic compound for research related to life sciences and the catalog number is T65356.

(S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T65672 and the CAS number is 106939-34-8.

(S)-N-(2-Amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)propionamide is a useful organic compound for research related to life sciences. The catalog number is T65667 and the CAS number is 106006-84-2.

(S)-S-Benzyl 6-amino-2-(((benzyloxy)carbonyl)amino)hexanethioate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65508 and the CAS number is 69861-89-8.

(S,E)-2-Methyl-6-(p-tolyl)hept-3-en-2-ol is a useful organic compound for research related to life sciences and the catalog number is T125520.

(2S,3R,4S,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol is a useful organic compound for research related to life sciences and the catalog number is T67174.

t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate is a useful organic compound for research related to life sciences. The catalog number is T66069 and the CAS number is 147489-06-3.

(S,E)-2-Amino-6-(but-2-enamido)hexanoic acid is a useful organic compound for research related to life sciences and the catalog number is T64505.

5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine . It is formed from (S)-duloxetine via a 5- or 6-hydroxy duloxetine intermediate, which is formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6, and a catechol duloxetine intermediate. 5-hydroxy-6-methoxy (S)-Duloxetine binds to the serotonin (5-HT), norepinephrine, and dopamine transporters with Ki values of 266, 920, and 2,814 nM, respectively.

(S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65610 and the CAS number is 154127-42-1.

2'-Deoxy-2'-fluoro-6-S-Methyl-6-thio-ara-guanosine is a Nucleoside Derivative - 6-Modified purine nucleoside; Thio-nucleoside; Fluoro-modified nucleoside.

(S)-tert-Butyl 2-amino-6-(((benzyloxy)carbonyl)amino)hexanoate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65633 and the CAS number is 5978-22-3.

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65199 and the CAS number is 146987-10-2.

(S)-2-Amino-5-((2,2,10,10-tetramethyl-4,8-dioxo-3,9-dioxa-5,7-diazaundecan-6-ylidene)amino)pentanoic acid is a useful organic compound for research related to life sciences and the catalog number is T64690.

Acetonitrilebis[2-diphenylphosphino-6-t-butylpyridine]cyclopentadienylruthenium(II) hexafluorophosphate is a useful organic compound for research related to life sciences and the catalog number is T67238.

2'-Deoxy-2'-fluoro-6-S-methyl-6-thio-arabino-inosine is a Nucleoside Derivative - 6-Modified purine nucleoside; Thio-nucleoside; Fluoro-modified nucleoside.

(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T65424 and the CAS number is 100986-89-8.

(S)-1-(6-Amino-9H-purin-9-yl)propan-2-ol is a useful organic compound for research related to life sciences. The catalog number is T66343 and the CAS number is 14047-27-9.

5(S),6(S)-DiHETE is one of the four diastereomeric 5,6-dihydroxy acids produced from the non-enzymatic hydrolysis of LTA4. 5(S),6(S)-DiHETE does not have significant leukotriene-like activity.