(rac)cp601927 hydrochloride

(Rac)-CP-601927 hydrochloride is the racemate form of CP-601927, a nicotinic acetylcholine receptor (nAChR) agonist, with Ki values of 1.2 nM for α4β2 and 102 nM for α3β4 nAChR.

CP-547632 hydrochloride is a well-tolerated and orally-bioavailable inhibitor of the VEGFR-2 and basic FGF kinases (IC50s: 11 nM and 9 nM) with antitumor efficacy.

CP-96021 hydrochloride is a potent and orally active antagonist of leukotriene D4 (LTD4) platelet activating factor receptor (Kis: 34 nM and 37 nM).

CP-24879 hydrochloride (CP-24879 HCl), a Δ5D/Δ6D dual-inhibitor, can significantly reduce intracellular lipid accumulation and inflammatory injury in hepatocytes. CP-24879 hydrochloride exhibits superior antisteatotic and anti-inflammatory actions in fat-1 and ω-3-treated hepatocytes.

CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist with pEC50 values of 9.96 for human 5-HT2C, 7.19 for 5-HT2B, and 6.81 for 5-HT2A receptors.

CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stability than CP-610431.

rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of propranolol that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol). It also demonstrates potent vasodilator activity (0.20 potency relative to propranolol; pA2 = 7.58).

rac-Desethyl oxybutynin is an active metabolite of the muscarinic acetylcholine receptor (mAChR) antagonist oxybutynin .1,2,3rac-Desethyl oxybutynin is formed from oxybutynin by the cytochrome P450 (CYP) isoform CYP3A4.2It binds to mAChRs in isolated rat bladder, submaxillary gland, heart, and colon with Kivalues of 5.38, 3.12, 16, and 5.59 nM, respectively.rac-Desethyl oxybutynin (0.4 and 0.8 mg/kg) reduces micturition pressure in rats.3

rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.

CP-409092 hydrochloride, a partial agonist of the GABAA receptor, exhibits anti-anxiety activity.

CP-100356 hydrochloride is an orally active, low micromolar dual inhibitor of MDR1 (P-gp) and BCRP, a nucleotide-derived substrate analogue that inhibits MDR1-mediated Calcein-AM and BCRP-mediated Prazosin transporters. Additionally, CP-100356 inhibits OATP1B1 and induces stomatal opening in the dark.

rac threo-Dihydro Bupropion-d9 Hydrochloride is a deuterated compound of rac threo-Dihydro Bupropion Hydrochloride. rac threo-Dihydro Bupropion Hydrochloride has a CAS number of 1396889-62-5.

(Rac)-IBT6A hydrochloride is a racemic mixture of IBT6A hydrochloride, an impurity of Ibrutinib, involved in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct [1]. IBT6A is related to Ibrutinib, a selective and irreversible Bruton's tyrosine kinase (Btk) inhibitor with an IC50 of 0.5 nM [2].

LNK754 is a farnesyltransferase inhibitor. It is used for the treatment of cancer and Alzheimer's disease.

CP 122721 hydrochloride is a potent and selective non-peptide (nonpeptide) neurokinin NK1 antagonist, demonstrating a pIC50 of 9.8 against the human NK1 receptor in IM-9 cells. It exhibits anxiolytic and antidepressant-like effects, as evidenced in studies [1] [2].

(Rac)-IBT6A hydrochloride is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib. IBT6A can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct. Ibrutinib is a Btk inhibitor (IC50: 0.5 nM).

KV1.3 channel antagonist

(Rac)-Atomoxetine D7 hydrochloride is a deuterium labeled (Rac)-Atomoxetine hydrochloride. (Rac)-Atomoxetine hydrochloride is a racemic form of Atomoxetine hydrochloride.

rac NorMetanephrine-d3 Hydrochloride is a deuterated compound of rac NorMetanephrine Hydrochloride.

rac-Paroxetine-d4 Hydrochloride is a deuterated compound of rac-Paroxetine Hydrochloride. rac-Paroxetine Hydrochloride has a CAS number of 78246-49-8. Paroxetine hydrochloride is a serotonin uptake inhibitor that is effective in the treatment of depression.

rac Atomoxetine-d5 Hydrochloride is a deuterated compound of rac Atomoxetine Hydrochloride. rac Atomoxetine Hydrochloride has a CAS number of 82857-40-7.

(Rac)-5-Hydroxymethyl Tolterodine hydrochloride, also known as (Rac)-Desfesoterodine hydrochloride, is an active metabolite of Tolterodine that functions as a mAChR antagonist. It exhibits significant affinity (K i values) for M1, M2, M3, M4, and M5 receptors, with values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM, respectively. This compound is commonly employed in research related to overactive bladder conditions.

CP-601927 is a nicotinic acetylcholine receptor (NACHR) agonist with permeability, high affinity, and selectivity.

rac Metanephrine-d3 Hydrochloride Salt is a deuterated compound of rac Metanephrine Hydrochloride Salt.

(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine, a full agonist of the dopamine receptor and a partial agonist of the 5-HT1A receptor.