aldch2peg10boc

Methyl 2-(Boc-aMino)-2-(oxetan-3-yl)acetate can be used as a building block for the synthesis of various biologically active molecules such as peptides, proteins, and nucleic acids.

NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = 10.19).

Hydroxy-PEG4-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC.

Ald-CH2-PEG10-Boc is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

2-Caren-10-ol is a useful organic compound for research related to life sciences and the catalog number is T124382.

(2-Pyridyldithio)-PEG2-Boc is a polyethylene glycol-based PROTAC linker used in the synthesis of PROTACs [1].

SARS-CoV-2-IN-10 is a powerful and non-toxic inhibitor of SARS-CoV-2 3CL protease, with IC50 and EC50 values of 0.13 nM and 1.03 nM, respectively. The SARS-CoV-2 3C-like protease (3CLpro) is critical for viral replication and serves as an ideal target for intervention. By targeting the SARS-CoV-2 3CL protease, SARS-CoV-2-IN-10 has the potential to facilitate the development of effective antiviral drugs specific to SARS-CoV-2.

Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker used for the synthesis of PROTACs [1].

SARS-CoV-2 3CLpro-IN-10(5d) is a potent inhibitor of the SARS-CoV-2 3CL protease with an IC50 value of 190 nM and demonstrates broad-spectrum antiviral activity, exhibiting IC50 values of 790 nM for SARS-CoV-1 and 70 nM for MERS-CoV.

Boc-2-Pal-OH is an amino acid derivative and has a wide range of applications in life science related research.

Boc-NH-PEG-amine (MW 3400) is a PEG-based PROTAC linker used in PROTAC synthesis[1].

(E/Z)-10-Hydroxy-2-decenoic acid is a useful organic compound for research related to life sciences. The catalog number is T124254 and the CAS number is 765-01-5.

Boc-10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

20)abeotaxa-4(20),11-dien-10-one'>2alpha,7beta,13alpha-Triacetoxy-5alpha-cinnamoyloxy-9beta-hydroxy-2(3->20)abeotaxa-4(20),11-dien-10-one is a natural product for research related to life sciences. The catalog number is TN2840 and the CAS number is 322471-42-1.

SARS-CoV-2 Mpro-IN-10 (27h) is a potent inhibitor of the Mpro enzyme, with IC50 and EC50 values of 10.9 nM and 43.6 nM, respectively. It is used in research on the SARS-CoV-2 virus [1].

VEGFR-2-IN-10 has enhanced antiangiogenic potency against VEGFR2 phosphorylation induced by VEGF with an IC50 value of 0.7 μM and no cytotoxic effects.

Aristola-1(10),8-dien-2-one (Catalog No. TN3442, CAS No. 22391-34-0) is a natural product that can be used as a reference standard.

8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol, a chemical component of essential oils from Telekia speciosa, exhibits significant antiproliferative activity against human cancer cell lines in vitro.

Boc-Arg(Z)2-OH is an amino acid derivative and has a wide range of applications in life science related research.

Boc-(R)-2-thienylglycine, with catalog number T65017 and CAS number 74562-03-1, is a valuable organic compound for research in the life sciences.

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

11R,12-Dihydroxyspirovetiv-1(10)-en-2-one is a natural product for research related to life sciences. The catalog number is TN2593 and the CAS number is 62574-30-5.

Boc-Phe(2-Me)-OH is an amino acid derivative and has a wide range of applications in life science related research.

COX-2-IN-10 is a potent COX-2 inhibitor that exhibits inhibitory effects on the production of IL-6, TNF-α, and IL-1β, and inhibits PGE2 production in a concentration-dependent manner with an IC50 value of 2.54 μM. Additionally, COX-2-IN-10 inhibits the expression of iNOS and COX-2 at both mRNA and protein levels.

Boc-NH-PEG-amine (MW 2000) is a polyethylene glycol (PEG) linker utilized in PROTAC synthesis[1].

N-Boc-PEG-t-butyl ester is a PEG-based linker for PROTACs, joining two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system within cells.

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker, incorporating a cereblon ligand based on Thalidomide and a 3-unit PEG linker, specifically designed for PROTAC technology applications.

Boc-D-2-Pal-OH is an amino acid derivative with a wide range of applications in life sciences research.

Boc-D-2-Nal-OH is a useful organic compound for research related to life sciences. The catalog number is T66189 and the CAS number is 76985-10-9.

3,11,12-Trihydroxyspirovetiv-1(10)-en-2-one is a natural product for research related to life sciences. The catalog number is TN5344 and the CAS number is 220328-04-1.

3,11,12-Trihydroxyspirovetiv-1(10)-en-2-one is a natural product from Murraya exotica L

[(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one, a sesquiterpene from turmeric, is also known as (1(10)E,2R*,4R*)-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one.

Ammonium, diethylmethyl(2-(10-phenothiazinyl)ethyl)-, iodide is a biaoctive chemical.

Boc-2-Nal-OH is a useful organic compound for research related to life sciences. The catalog number is T66060 and the CAS number is 58438-04-3.

2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one is a natural product

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Boc-Lys(2-Cl-Z)-OH (Catalog number: T67521, CAS number: 54613-99-9) is an important organic compound utilized in life sciences research.

DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

3-(2'-Deoxyribofuranosyl)pyrimido(1,2-a)purin-10(3H)-one is a malondialdehyde-deoxyguanosine adduct.

Acridan-9-carboxylic acid, 10-methyl-, 2-(diethylamino)ethyl ester, hydrochloride is a biochemical.

Boc-D-Tyr(2-Br-Z)-OH, with catalog number T66218 and CAS number 81189-61-9, is a valuable organic compound for life sciences research.

Hydroxy-PEG1-(CH2)2-Boc is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis-targeting chimeric molecules (PROTACs)[1].

Boc-Tyr(2-Br-Z)-OH is a useful organic compound for research related to life sciences. The catalog number is T67623 and the CAS number is 47689-67-8.

Boc-D-Phe(2-Me)-OH, an amino acid derivative, has diverse applications in life science research.

Hydroxy-PEG2-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs).

Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker used in the synthesis of PROTACs [1].

Hydroxy-PEG3-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

2-Carene-10-al is a principal constituent of the essential oil extracted from Cuminum cyminum L. [1].

8-Hydroxy-9,10-diisobutyryloxy-thymol, a potent terpenoid found in Inula sericophylla [1], exhibits significant bioactivity.

11S,12-Dihydroxyspirovetiv-1(10)-en-2-one is a natural product for research related to life sciences. The catalog number is TN2594 and the CAS number is 62623-86-3.