anemone

Anemonin is a furanone dimer found in the Buttercup (Ranunculaceae) family. Anemonin has been shown to regulate tyrosinase-related proteins and mRNA in human melanocytes and may be useful in attenuting osteoarthritis progression.

Protoanemonin is a naturally occurring compound which may be isolated from plants of the family Ranunculaceae. Protoanemonin can also be produced by Pseudomonas sp.

Pulsatilla saponin D (Hederacolchiside A) has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer, and it inhibits cell growth via cell cycle arrest and apoptosis in various cancer cell types.

Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacolchiside A1 shows antiproliferation activities in three cancer cell lines with the IC50 value of 2.4 uM, it exhibits a preferential cytotoxicity on a pigmented melanoma cell line. It suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway.

Dipsacobioside is extracted from Anemone hupehensis.

Presapogenin CP4 extracted from Anemone hupehensis.

Anhuienside F, a natural product, is isolatable from the root of Anemone vitifolia Buch.-Ham. [1].

12-Oxograndiflorenic acid, a natural product extractable from Anemone and Porphyra, exhibits cytotoxicity against certain cells.

Raddeanoside 20 can slightly suppress the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP) in a concentration dependent manner.

Flaccidoside II, an active triterpenoid saponin from Anemone flaccida rhizome, both inhibits proliferation and induces apoptosis in Malignant Peripheral Nerve Sheath Tumors (MPNSTs) cell lines and ameliorates collagen-induced arthritis in mice [1] [2].

Prosapogenin CP6 is a natural product

Huzhangoside B is a natural product of Anemone, Ranunculaceae. The catalog number is TN4230 and the CAS number is 94795-70-7. Huzhangoside B can be used as a reference standard.

Leonloside D is a natural product

Raddeanoside R16, an oleanane-type saponin, can be isolated from the rhizome of Anemone raddeana [1].

Raddeanoside R8 is a natural product from Anemone raddeana Regel.

Raddeanin A (NSC-382873) has moderate inhibitory activity against histone deacetylases (HDACs). Raddeanin A has high antiangiogenic potency, antitumor activity.

Huzhangoside D shows insecticidal activities against termite (Coptotermis homii), the LC50 of 0.2 mg/mL.

Glycoside St-J (Compound 2), a triterpenoid saponin isolated from Anemone flaccida, exhibits antitumor activity by inhibiting HeLa cell proliferation and shows potential for use in the development of novel anticancer agents [1].