anti-TB agent 1 is a potent and orally active anti-tuberculosis agent (MICs: < 2 nM against the Mtb strains H37Rv, rRMP and rINH).

Anti-inflammatory agent 15 (compound 29) is a potent antimycobacterial agent that can be used in the research of tuberculosis (TB). Anti-inflammatory agent 15 inhibits the growth of Mtb H37Rv and M299 with MIC50 of 2.3 and 7.8 μM, respectively. Anti-inflammatory agent 15 (compound 29) is also an anti-inflammatory agent that inhibits NO by suppressing the expression of iNOS and also inhibited the production of TNF-α and IL-1β [1].

4-Piperidinecarboxamide is a mycobacterial aspartyl-tRNA synthetase (AspS) inhibitor and a potential anti-tuberculosis (TB) agent [1].

Anti-inflammatory agent 11 (compound 16) is a potent antimycobacterial agent that can be used in the research of tuberculosis(TB). Anti-inflammatory agent 11 inhibits the growth of Mtb H37Rv and M299 with MIC 50 of 1.3 and 6.9 μM, respectively. Anti-inflammatory agent 11 is also an anti-inflammatory agent that inhibits NO through the suppressing expression of iNOS and also inhibited the production of TNF-α and IL-1β [1].

Antibacterial agent 121 (Compound 10) demonstrates antibacterial properties and exhibits efficacy against mycobacterial strains while also possessing anti-inflammatory activity. This compound finds potential applications in Tuberculosis (TB) research [1].