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azd-9291 mesylate

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    2
    TargetMol | Activity
Osimertinib mesylate
Mereletinib mesylate,AZD-9291 mesylate
T36341421373-66-1
Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib mesylate has antitumor activity for the treatment of EGFR-mutated non-small-cell lung cancer.
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TargetMol | Citations Cited
AZD-8529 mesylate
T10432L1314217-69-0
AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
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