STC314 is an anti-infective agent that reverses organ damage caused by excessive immune response by neutralizing extracellular histones and neutrophil trapping networks, and can be used in the study of sepsis and acute respiratory distress syndrome (ARDS).STC314 protects the stability of lipid bilayers, and inhibits platelet activation and erythrocyte damage.STC314 is also used in the study of prostate cancer.Nardeterol HCl is a selective kappa agonist with analgesic activity.

DPPC (129Y83) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes.

MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2. Like the related compound MitoTEMPO , MitoTEMPOL combines an antioxidant moiety (here, TEMPOL, also known as 4-hydroxy-TEMPO) with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. MitoTEMPOL has been used to elucidate the role of mitochondria-derived superoxide in mitochondrial, cellular, and whole animal signaling.

β-Amyloid(28-35) human is a neurotoxic β-amyloid peptide fragment that contributes to Alzheimer's disease pathogenesis by interacting with neuronal membranes, modulating its secondary structure and toxicity. It also exhibits anisotropic effects on the acidic phospholipid DPH, thereby increasing the internal fluidity within lipid membrane bilayers [1].

PA22-2 (free acid) (Cys-Laminin A chain 2091-2108), a peptide, promotes neurite outgrowth and facilitates the formation of neuron-like processes. It is utilized in the culturing of human adenoid cystic carcinoma cells and the development of peptide-functionalized supported phospholipid bilayers [1] [2] [3].

1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation of glycosphingolipid antigens into DPPC-containing liposomes increases the immunogenicity of the antigens in mice.4 |1. Ege, C., and Lee, K.Y.C. Insertion of Alzheimer's Aβ40 peptide into lipid monolayers. Biophys. J. 87(3), 1732-1740 (2004).|2. Leekumjorn, S., and Sum, A.K. Molecular simulation study of structural and dynamic properties of mixed DPPC/DPPE bilayers. Biophys. J. 90(11), 3951-3965 (2006).|3. Kalra, V.K., Sikka, S.C., and Sethi, G.S. Transport of amino acids in γ-glutamyl transpeptidase-implanted human erythrocytes. J. Biol. Chem. 256(11), 5567-5571 (1981).|4. Uemura, A., Watarai, S., Iwasaki, T., et al. Induction of immune responses against glycosphingolipid antigens: Comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J. Vet. Med. Sci. 67(12), 1197-1201 (2005).

1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid. It has been used in PEGylated polyamidoamine-dendrimer-conjugated supported lipid bilayers (SLB) to isolate circulating tumor cells and tumor cell microembolis from patient-derived blood by antibody-coated microfluidics. [1] It has also been used as a component of SLBs to detect protein-ligand binding with ortho-conjugated Texas Red DHPE. [2] In addition, 1,2-dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) has been used in SLBs partitioned into nanowells to create DNA curtains, which can be used as a high-throughput tool for detection of protein-DNA interactions at the single molecule level.[3]

PEP1 is a biologically active peptide that interacts with POPC supported lipid bilayers (SLBs), binding at low concentrations, while higher concentrations induce POPC SLB lysis.

DSPE-PEG-Folate (Mw 3350), a derivative of PEG with folic acid content, exhibits targeting capability by binding to folate receptors on cancer cells. It forms micelles/lipid bilayers, facilitating its use in targeted drug delivery system research [1] [2] [3].

1,3-Dipalmitoleoyl-rac-glycerol is a diacylglycerol with palmitoleic acid at the sn-1 and sn-3 positions. It selectively inhibits α-glucosidase from S. cerevisiae over rat enzyme (IC50s = 4.45 and 9,326.5 μM, respectively). 1,3-Dipalmitoleoyl-rac-glycerol has been used in the formation of lipid bilayers to study the effects of membrane composition and the ionophore valinomycin on membrane potential.

DGDG, a chloroplast lipid pivotal for photosynthesis, forms bilayers and has applications in drug delivery [1].

1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) (DMPC) is a synthetic phospholipid used in liposomes which is used for the study of lipid monolayers and bilayers[1].

DSPE-SPDP, a phospholipid molecule, possesses the ability to form lipid bilayers in water, making it valuable for biochemical research [1].

4'-Methoxyflavonol is a flavone/flavonol compound that has been synthetically produced. It exhibits a structure with 1, 2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayers.

1,2-O-Dioctadecyl-rac-glycerol, a saturated dialkyl glyceryl ether featuring octadecyl groups at the sn-1 and sn-2 positions, closely resembles the structure of diacylglycerol. This similarity allows its use in model lipid bilayers to explore the dynamics of different biological membrane compositions.

Propoxycaine hydrochloride, an ester local anesthetic, inhibits voltage-gated sodium channels, modulates nerve impulses, and can induce sensory loss.Propoxycaine hydrochloride modulates the flow of lipid bilayers in SPMVs.

1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)) can be used in lipid mixtures with DOPC and DOPE as effective nontoxic and nonviral DNA vectors. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium has been used in the formation of unilamellar vesicles to study the effect of curvature on membrane structure and in the formation of supported lipid bilayers to study the effects of various support materials on lipid redistribution between membrane leaflets.

1-Palmitoyl-2-lauroyl-sn-glycero-3-PC (1,2-PLPC) is a phospholipid with palmitoyl (16:0) and lauryl (12:0) acyl chains at the sn-1 and sn-2 positions, respectively. This mixed-chain phosphatidylcholine aids in researching the role of chain-chain contact interactions in maintaining the structural stability of lipid membrane bilayers.

Sulforhodamine 101 DHPE, a fluorescent probe, results from the conjugation of sulforhodamine 101, a red fluorescent dye with excitation/emission spectra of 586/605 nm, to the phospholipid 1,2-dipalmitoyl-sn-glycero-3-PE. It effectively integrates into phospholipid bilayers and is utilized for imaging solid supported lipid bilayers, detecting protein-ligand interactions on bilayers, and monitoring lipid probe colocalization in liposomes through resonance energy transfer (RET).

DSPE-PEG-SH (MW 2000), a pegylated phospholipid featuring a reactive thiol group for forming covalent thioether linkages with maleimide, is an amphiphilic polymer capable of self-assembling into lipid bilayers in aqueous solutions. It is utilized in encapsulating agents within drug delivery systems, including mRNA vaccines.

1,2-Dilauroyl-sn-glycerol ((S)-1,2-Dilaurin) is primarily composed of the interaction of 1,2-dilauroyl-sn-glycerol (1,2-DLG) with phosphatidylcholine (PC) bilayers.

MitoTEMPO is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties.[1] This compound combines the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. Mitochondrial targeting of superoxide scavenging via mitoTEMPO has been examined for potential therapeutic benefit to a variety of mitochondrial dysfunctions arising from excessive reactive oxygen species.[2][3][4]

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) is a phospholipid ubiquitous in cell membranes, with compositions in the range 0-60 mol% cholesterol.

DPhPC is a synthetic liposome used to synthesize liposomes commonly used in artificial membrane matrices.DPhPC bilayers do not allow ion leakage in the absence of pore/ion channels.DPhPC can be used to study channel proteins and membrane structure.

DSPE-PEG-Folate (MW 5000), a derivative of polyethylene glycol (PEG) integrated with folic acid, demonstrates a specific targeting ability by binding to folate receptors on cancer cells. This compound forms micelles/lipid bilayers, facilitating its application in targeted drug delivery system research [1] [2].