biotin lc lc nhs

Sulfo-NHS-LC-Biotin, or Sulfosuccinimidyl 6-(biotinamido) Hexanoate, is a long-chain water-soluble biotinylating agent that targets cell surface proteins and is reactive to primary amine groups.

Biotin-LC-LC-NHS is a SMCC cross-linking reagent, which serves as a labeling agent for antibodies and small molecules, like Paclitaxel.

Sulfo-NHS-LC-Biotin sodium is an amine-reactive biotinylation reagent for antibody labeling.

Sulfo-NHS-Biotin (Biotin-NHS) is a water-soluble biotinylation reagent used in Biotin-Streptavidin binding reactions. Sulfo-NHS-Biotin is particularly useful for targeting cell surface proteins in Streptavidin-Biotin assays. It can be used for protein detection or immobilization when used in conjunction with streptavidin and Immobilized Streptavidin.

Negative control for LC 2.

Sulfo-LC-SPDP is a heterobifunctional crosslinker characterized by its thiol-cleavable and membrane impermeable properties.

N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker suitable for synthesizing PROTACs[1].

NHS-SS-biotin is a cleavable linker vital in ADC synthesis. NHS-SS-biotin joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.

Biotin-bis-amido-SS-NHS is an alkyl/ether-based PROTAC linker that finds utility in the synthesis of PROTACs.

LC kinetic stabilizer-1 is a potent, selective kinetic stabilizer for amyloidogenic immunoglobulin light chains, demonstrating EC50 values of 140 nM for WIL-FL* and 74.1 nM for WIL-FL*T46L/F49Y, respectively. Notably, WIL-FL represents an amyloidogenic FL LC dimer.

Biotin-PEG2-NHS ester is a biotinylated, polyethylene glycol (PEG)-based linker, which is utilized in PROTAC synthesis for the purpose of biotin attachment[1].

LC-1310 is an irreversible p97 inhibitor.

Biotin LC hydrazide (BACH) is a modification reagent of long-chain protein. Biotin LC hydrazide transforms periodate-oxidized glycoproteins and can be used to target glycoproteins and glycans.

LC-2 (PROTAC KRASG12C Degrader-LC-2) is a novel von Hippel-Lindau-based PROTAC degrader of endogenous KRAS G12C with a DC50 between 0.25 and 0.76 μM.LC-2 is a PROTAC that covalently binds KRAS G12C with MRTX849 and recruits the E3 ligase, VH, to induce a rapid and sustained degradation of KRAS G12C. LC-2 inhibits MAPK signaling in pure and heterozygous KRAS G12C cell lines.

Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Iodoacetyl-LC-Biotin reacts with sulfhydryl groups to form stable thioether linkages.

Biotin-C5-NHS Ester is an alkyl/ether-based linker for PROTAC synthesis[1].

FITC-LC-TAT (47-57) is a fluorescein isothiocyanate (FITC)-labeled trans-activator of transcription (TAT) peptide, which is recognized as a cell-penetrating peptide (CPP). This compound enhances the yield and solubility of heterologous proteins [1].

Biotin-PEG4-NHS ester is a biotinylated and PEGylated N-hydroxysuccinimide ester. It serves as a linker in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Biotin-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

LC 6 is an orally active antiallergic agent.

Biotin-PEG9-NHS Ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin NHS (NHS-Biotin) is an amino reactive biotin reagent used to prepare biotinylated surfaces or polypeptides.

LC-1028 is a novel potent selective, covalent and irreversible inhibitor of p97 (valosin-containing protein) with IC50 =33 nM.

Biotin-PEG6-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].

Biotin-PEG8-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-C10-NHS Ester is an alkyl/ether-based linker compound utilized in the synthesis of PROTACs[1].

PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of ferroptosis. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 μM in a cell-free assay, and at a concentration of 61 μM in wild-type, but not Gpx4-/-, mouse embryonic fibroblast (MEF) extracts.PKUMDL-LC-101-D04 (200 μM) reduced cholesterol peroxide-induced MEF death.

PC-Biotin-PEG4-NHS carbonate is a polyethylene glycol (PEG) derived linker employed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM.

LC-R 505 is an anti-inflammatory.

Biotin-PEG3-NHS ester is a PROTAC linker based on the PEG structure and can be used to prepare PROTAC.

PC Biotin-PEG3-NHS ester is a cleavable ADC linker comprising three PEG units. This linker is specifically designed for use in the synthesis of antibody-drug conjugates (ADCs)[1].