bis-peg-3-t-butyl ester

Bis-PEG3-t-butyl ester, a PEG-based linker for PROTACs, joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a polyethylene glycol (PEG)-based PROTAC linker used in the synthesis of PROTACs[1].

1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl ether-based PROTAC linker used in the synthesis of PROTACs [1].

DBCO-NHS ester 3 (Compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (ADC). It is a derivative of Dibenzylcyclooctyne (DBCO) resulting from the activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2].

Azido-PEG3-S-PEG4-t-butyl ester, a PEG-based PROTAC linker, is used in PROTAC synthesis [1].

Bis-PEG-TFP ester (MW 5000) is a polyethylene glycol (PEG) based linker compound utilized in synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].

Bis-PEG17-NHS ester is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker used for synthesizing PROTACs [1].

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a polyethylene glycol (PEG)-based linker used for PROTAC synthesis [1].

N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Bis-PEG4-NHS ester is a noncleavable, 4-unit PEG linker used for antibody-drug conjugation (ADC).

FmocNH-PEG4-t-butyl ester is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the selective degradation of proteins through the ubiquitin-proteasome system within cells.

PEG4-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derivative functioning as a linker in PROTAC synthesis, specifically designed for creating proteolysis-targeting chimeras (PROTACs)[1].

Bis-PEG13-NHS ester, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

Fluorescein-PEG6-bis-NHS ester, a polyethylene glycol (PEG)-based linker, is utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker characterized by its PEG composition, crucial in synthesizing various PROTACs, including BI-3663, a selective PTK2 FAK PROTAC. Using cereblon ligands, it targets E3 ligases to degrade PTK2, exhibiting potent inhibitory activity with an IC50 of 18 nM[1].

t-Butyl acetate-PEG3-CH2COOH is a polyethylene glycol-derived PROteolysis TArgeting Chimera (PROTAC) linker designed for incorporation into the synthesis of PROTAC molecules.

N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Bis-PEG2-NHS ester, utilized in antibody-drug conjugation (ADC), functions as a non-cleavable linker with two polyethylene glycol (PEG) units.

t-Butyl acetate-PEG2-CH2COOH (catalog number T64491) is a valuable organic compound for life sciences research.

Azido-PEG15-t-butyl ester is a polyethylene glycol (PEG) derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a polyethylene glycol (PEG) derivative designed as a linker for PROTAC synthesis [1].

FmocNH-PEG4-t-butyl acetate is a polyethylene glycol (PEG)-derived PROTAC linker used in the synthesis of PROTACs, which are bifunctional molecules designed to degrade target proteins.

DOTA-(t-butyl)3-PEG5-azide is a polyethylene glycol (PEG)-derived linker specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Bis-PEG7-NHS ester is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

Bis-PEG4-PFP ester is a PEG-based linker for PROTACs, joining two essential ligands and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

C6-Bis-phosphoramidic acid diethyl ester is an alkyl chain-derived PROTAC linker suitable for PROTAC synthesis [1].

Ms-PEG10-t-butyl ester is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

N-DBCO-N-bis(PEG2-C2-NHS ester) is a Polyethylene Glycol (PEG) derived linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Bis-PEG5-NHS ester, a cleavable ADC linker, is used in the synthesis of antibody-drug conjugates (ADCs) [1].

Bis-PEG2-PFP ester is a non-cleavable 2-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs) [1]. Additionally, Bis-PEG2-PFP ester serves as a PEG-based linker for the synthesis of proteolysis targeting chimeras (PROTACs) [2].

N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs).

N-Boc-N-bis(PEG4-NHS ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of PROTACs [1].

Bis-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Bis-PEG1-PFP ester is a non-cleavable ADC linker with a 1-unit PEG moiety, designed for synthesizing antibody-drug conjugates (ADCs) [1].

Ms-PEG5-t-butyl ester is a PEG-based linker for PROTACs that connects two critical ligands essential for creating PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Amino-PEG7-t-butyl ester is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

N-Mal-N-bis(PEG4-NHS ester) is a polyethylene glycol (PEG)-based bifunctional linker used for synthesizing Proteolysis Targeting Chimeras (PROTACs) [1].

Benzyl-PEG6-t-butyl ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NHS-PEG4-(m-PEG12)3-ester is a polyethylene glycol (PEG)-based linker used for PROTAC synthesis [1].

Bis-PEG13-PFP ester, a PEG-based linker for PROTACs, joins two essential ligands to form PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Desthiobiotin-N-bis(PEG4-t-butyl ester) is a PEG-based linker compound used in the synthesis of PROTACs, which are bifunctional molecules aimed at targeted protein degradation[1].

Bis-PEG9-NHS ester, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

Bis-PEG25-NHS ester is a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].

t-Boc-Aminooxy-PEG4-NHS ester is a polyethylene glycol (PEG) derivative that functions as a linker for PROTAC synthesis [1].

Bis-PEG3-NHS ester is a noncleavable 3-unit PEG linker used in antibody-drug conjugation (ADC).

Bis-PEG6-t-butyl ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor used as a toxin payload in antibody-drug conjugates, is conjugated via a DBCO-(PEG)3-vc-PAB linker.

Bis-PEG10-NHS ester, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

Bis-Mal-Lysine-PEG4-TFP ester, a PEG-based PROTAC linker, facilitates PROTAC synthesis[1].