Elomotecan (BN 80927 free base), a camptothecin analog from the homocamptothecin family (hCPT), serves as a potent inhibitor of topoisomerases I and II. It effectively reduces the proliferation of various tumor cells more significantly than other reference anticancer drugs targeting the same topoisomerases [1].This compound is unstable in powder form and other related salt forms are recommended.

Elomotecan hydrochloride (BN 80927), a camptothecin analog from the homocamptothecin family (hCPT), is a highly potent inhibitor of both topoisomerases I and II. It demonstrates superior efficacy in reducing the proliferation of various tumor cells compared to other reference anticancer drugs targeting these topoisomerases.