cucurbitacin b

Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inhibitor of HIF-1 and provide new perspectives into the mechanism of its anticancer activity. Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung Y cells.

Cucurbitacin B 2-o-α²-D-glucoside has anticancer activity.

2-epi-Cucurbitacin B, a natural product, is derived from Ecballium elaterium L. XVI. [1].

Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2 STAT3 with anti-cancer activity.

Cucurbitacin A 2-O-β-D-glucopyranoside is a natural product for research related to life sciences. The catalog number is TN5974 and the CAS number is 1135141-76-2.