cyclo-l-trp-l-trp

Cyclo-L-Trp-L-Trp is a broad-spectrum antifungal. It also induces a high degree of acetylation of histones.

L-Cystine dihydrochloride is an Nrf2 inducer with whitening and anti-dark spot effects.L-Cystine dihydrochloride has cytoprotective effects in cells, and is often added to various fungal cultures as a carbon source.

H-Lys-Trp-Lys-OH acetate is a peptide with antibacterial and antiviral activities.

N-Cbz-L-Leucine (N-[(Phenylmethoxy)carbonyl]-L-leucine) is a leucine derivative, a commonly used amino acid protecting group.

pGlu-K(-NBD)-Q-R-L-G-N-Q-W-A-V-G-H-L-M-N is a peptides

L-Cyclohexylalanine (L-3-Cyclohexylalanine) is an amino acid analog that binds to the heavy enzyme thioester of the short peptide S synthase.L-Cyclohexylalanine can be used to synthesize anticoagulant decapeptides.

pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val is a peptides

L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is involved in the rearrangement of protein disulfide bonds and the reduction of peroxides.

L-Tryptophanylglycine (Trp-gly), a dipeptide, inhibits Ceronapril uptake in Caco-2 cells with an inhibition constant (K i) of 7.19 mM [1].

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate), an antagonist for Substance P and Bombesin, modulates ocular inflammatory responses triggered by antidromic trigeminal nerve stimulation [1].

L-Cysteinesulfinic acid monohydrate is a potent agonist at rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92, 4.6, 3.9, 2.7, 4.0, and 3.94 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively[1].

Glycyl-L-valine is a dipeptide composed of glycine and valine. It is an incomplete breakdown product of protein digestion or protein catabolism.

Boc-D-Trp(For)-OH, a derivative of the amino acid tryptophan with pharmacological properties such as inhibition of growth hormone release, induction of sleep, and anti-inflammatory effects [1] [2], is synthesized through the ammonolysis of Boc-protected D-alanine, followed by cyclization with ninhydrin to form the dipeptide.

Nα,Nα-Bis(carboxymethyl)-L-lysine is a potent competitive inhibitor of bitter taste receptor 4, exhibiting an IC50 of 59 nM. This compound finds application in studies related to bitter taste receptors [1] [2] [3].

HS-(CH2)3CO-L-Ala-D-Ala-L-Ala-NH-CH2-S-(CH2)5-CO-DM is a peptide-cleavable agent-linker conjugate utilized in antibody-drug conjugates (ADCs), with the DM denoting the maytansinoid component [1].

H-Lys-Trp-OH (KW) is an ACE inhibitory peptide with an IC 50 of 7.8 μM [1] .

L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide. It has been used as a biomarker for reduced nitric oxide formation in patients with cardiovascular disease and metabolic syndrome.

Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized form of GSH . It can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase. GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications. The ratio of reduced glutathione to oxidized glutathione within cells is often used as an indicator of oxidative stress, with higher concentrations of GSSG predicting increased oxidative stress.

Several different arachidonoyl amino acids, including N-arachidonoyl-L-alanine (NALA), have been isolated and characterized from bovine brain. The glycine congener (NAGly) was further characterized and found to suppress formalin-induced pain in rats. NALA may have activity at cannabinoid receptor and/or VR1, but has not been fully characterized to date.

L-Glutamic γ-monohydroxamate is an antitumor compound that impedes cell proliferation and selectively hinders L-histidine uptake in microvascular endothelial cells. Additionally, this compound serves as a vanadium ligand, enhancing glucose uptake and metabolism, leading to reduced blood glucose levels in vivo [1] [2] [3].

Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM); blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.

N-Oleoyl-L-Serine (N-Oleoylserine) is an endogenous long-chain fatty acid amide that is a lipid modulator of bone remodeling and stimulates osteoclast apoptosis which can be used to study osteoporosis. N-Oleoyl-L-Serine showed high activity in an osteoblast proliferation assay.N-Oleoyl-L-Serine promotes osteoclast apoptosis by inhibiting Erk1 2 phosphorylation and expression of nuclear κB ligand (RANKL) receptor activator in bone marrow stromal cells and osteoblasts, which attenuates osteoclast populations.

L-GO-203 TFA is a potent inhibitor of the MUC1-C oncoprotein, serving as an anticancer peptide that targets intracellular proteins [1].

S-(2-Carboxyethyl)-L-cysteine (S-Carboxyethylcysteine), a modified sulfur amino acid, occurs naturally in Acacia seeds. This compound influences protein utilization in rats and suppresses methionine-induced growth rates while adversely affecting plasma amino acid concentrations in these animals [1].

DOTA-CXCR4-L, a peptide targeting the CXCR4 receptor, is utilized in cancer research, notably in the contexts of glioblastoma and triple-negative breast cancer [1].

N2-(tert-Butoxycarbonyl)-Nw-nitro-L-arginine is a useful organic compound for research related to life sciences. The catalog number is T65255 and the CAS number is 2188-18-3.

Fmoc-L-(4-thiazolyl)-Alanine is a useful organic compound for research related to life sciences and the catalog number is T65194.

Glycyl-L-glutamic acid, acting as a neurotrophic factor (NF) in vivo, maintains AChE content and activity without directly influencing AChE synthesis. It may also prevent preganglionic neuronal degeneration [1] [2].

Maculosin is a secondary metabolite of fungi and bacteria.

L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and non-Hodgkin's lymphoma. It is given by injection into a vein, muscle, or under the skin.

inhibitor of both glial and neuronal uptake of glutamate, aspartate and cysteate.

Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1 [1] .

[8-L-arginine] deaminovasopressin (dAVP) is a vasopressin analog [1] .

L-R4W2 TFA acts as a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), demonstrating significant inhibitory activity with an IC50 value of 0.1 μM. This compound potentially offers powerful analgesic properties [1] [2].

N-((Allyloxy)carbonyl)-N-methyl-L-alanine, an alanine derivative, serves as a precursor for the synthesis of complement factor D inhibitors, which are key in researching immune system-related diseases [1].

L,L-Dityrosine hydrochloride, also known as o,o'-Dityrosine hydrochloride, is a compound found in acid hydrolysates of various biological materials, notably the insect cuticular resilin.

3-Chloro-L-alanine Hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67574 and the CAS number is 51887-89-9.

N-Boc-3,5-difluoro-L-phenylalanine is a useful organic compound for research related to life sciences. The catalog number is T65469 and the CAS number is 205445-52-9.

Fmoc-L-HoLys(Boc)-OH is a useful organic compound for research related to life sciences. The catalog number is T65197 and the CAS number is 194718-17-7.

The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley rat stomach assessed as decrease in 14CO2 production with activty value of 1.8 μM

L-Threonine methyl ester hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66418 and the CAS number is 39994-75-7.

Fmoc-L-Glu(2-phenylisopropyloxy)-OH is a useful organic compound for research related to life sciences. The catalog number is T66440 and the CAS number is 200616-39-3.

tert-Butyl ((benzyloxy)carbonyl)-L-tyrosinate is a useful organic compound for research related to life sciences. The catalog number is T65514 and the CAS number is 16881-33-7.

L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo in mouse brain preparations. L-Allylglycine (1.2 mmol/kg, i.p.) induces convulsions and decreases GABA concentration throughout the cerebellum, pons, medulla, striatum, cortex, and hippocampus in mice. Chronic administration (3.2 μg/0.5 μl per hour for 13 days) of L-allylglycine in rats increases locomotor activity in an open field test and impairs attention in the 5-choice serial reaction time task (5CSRTT). In vitro, L-allylglycine inhibits GAD only when used at high concentrations (1-80 mM). The more potent in vivo activity can be attributed to metabolic conversion of L-allylglycine to 2-keto-4-pentanoic acid, a more potent convulsant and GAD inhibitor.

Ethyl L-leucinate HCl has been used as a hypertrophic agent to monitor its effects on myotubes and has also been used as a component of PMG media for culturing yeast.

Lys-phe-phe-phe-ile-ile-trp-och3 is a hydrophobic peptide which reacts with lipid vesicles.

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butylthio)-L-cysteine is a useful organic compound for research related to life sciences. The catalog number is T66172 and the CAS number is 73724-43-3.

Fmoc-L-aspartic acid (Fmoc-Asp-OH) is an aspartic acid derivative.

Ethyl L-methionate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67583 and the CAS number is 2899-36-7.