cyclooctyne-o-amido-peg-2-pfp ester

Cyclooctyne-O-amido-PEG2-PFP ester is a two-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) as a non-cleavable linker.

2-O-α-D-Glucopyranosyl-L-ascorbic Acid (ASCORBYL GLUCOSIDE), a glucoside derivative of ascorbic acid, exhibits anti-cancer properties upon enzymatic conversion to ascorbic acid.

2-O-(α-D-Glucopyranosyl)glycerol (2-alphaGG) is present in certain bacteria and plants that thrive in harsh environments and may extend the lifespan of budding yeast and erythrosporidium by enhancing their osmotic response.

2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of antitumor activity. The anticancer mechanism of 2'-O-Methyl-5-iodouridine is dependent on the inhibition of DNA synthesis and induction of apoptosis.

2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM). 1.Migliaccio, G., Tomassini, J.E., Carroll, S.S., et al.Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitroJ. Bio. Chem.278(49)49164-49170(2003)

5-Bromo-2’,3’,5’-tri-O-acetyluridine is a purine nucleoside analog that is being explored to improve Alzheimer’s and Parkinson’s diseases.

2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.

Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-β-D-glucoside induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo, Tetrahydroxystilbene-2-O-β-D-glucoside treatment restores memory impairment, as assessed by the passive avoidance test, in SD, Aβ and KA mouse models. In the hippocampus of mice given Tetrahydroxystilbene-2-O-β-D-glucoside in their diet, levels of erythropoietin, PGC-1α and haemoglobin were increased. Treatment with Tetrahydroxystilbene-2-O-β-D-glucoside might be a therapeutic strategy for memory impairment in neurodegenerative disease, physiological ageing or traumatic brain injury.

Phthalic acid mono-2-ethylhexyl ester (Phthalic Acid Monooctyl Ester) is a major bioactive metabolite of diethylhexyl phthalate (DEHP), which inhibits the 17,20 lyase activity of CYP17. The Cyp17a1 gene is specifically targeted by MEHP, explaining the MEHP-induced suppression of steroidogenesis observed.

2'-O-(2-azidoethyl)adenosine is a purine nucleoside analog with potential antitumor activity. The activity of 2'-O-(2-azidoethyl)adenosine was associated with inhibition of DNA synthesis and apoptosis.

Eurycomanol 2-O-β-D-glucopyranoside, a natural diterpenoid compound, is extracted from Tongkat Ali.

Kaempferol-3-O-β-D-glucosyl(1-2)rhamnoside is a natural peoduct isolated from Arabian jasmine

2′-C-Methyl-6-O-methylinosine (2′-C-Methyl-6-O-methylinosine) is a hypoxanthine analog exhibiting diverse physical activities for researching various tumor diseases.

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite, an adenine nucleoside analog, has potential vasodilator and anticancer activities relevant to cancer research.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

(2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol is a useful research compound for many research applications, including the fields of chemistry and life sciences, among others.

2'',3''-Di-O-acetyl-5''-deoxy-5-fuluro-D-cytidine is a derivative of capecitabine.

2'-O-Methyl-2-thiouridine is a purine nucleoside analogue present in synthetic thermophilic bacterial tRNAs. 2'-O-Methyl-2-thiouridine is more selective for A than unmodified U.

Thalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, integrating a Thalidomide-based cereblon ligand with a linker, suitable for PROTAC synthesis.

Triclopyr 2-butoxyethyl ester (Triclopyr-butotyl) is a bioactive substance. Triclopyr 2-butoxyethyl ester shows toxicity to Apis mellifera.

(25R)-3β,17α-dihydroxy-5α- spirostan-6-one3-O-α-L- rhamnopyranosyl-(1→2)-β- D-glucopyranoside is a natural product isolated from the bulbs of Lilium brownii var. viridulum.

Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate incorporating a Thalidomide-based cereblon ligand and a 3-unit PEG linker, used in PROTAC technology.

Thalidomide-O-amido-PEG2-C2-NH2 TFA (E3 Ligase Ligand-Linker Conjugates 24 TFA) is a synthesized E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a 2-unit PEG linker, utilized in PROTAC technology.

Hederagenin-28-beta-D-glucopyranoside, a triterpenoid saponin isolated from Ilex cornuta, protects against H2O2-induced damage in cardiomyocytes.

Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker suitable for use in PROTAC synthesis [1].

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride, incorporating an E3 ligase ligand and a linker, can be used as an immunomodulator for the treatment of cancer.

Boc-NH-O-C1-NHS ester, an alkyl ether-based PROTAC linker, is utilized in PROTAC synthesis.

(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside ((-)-Syringaresnol-4-O-beta-D-apiofuranos) is a lignan glycoside derived from the bark of Albizzia myriophylla.

Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) is a synthesized E3 ligase ligand-linker conjugate incorporating a Thalidomide-based cereblon ligand and a linker used in PROTAC technology.

Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA) is a synthesized E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker.

Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) is a synthesized compound that functions as an E3 ligase ligand-linker conjugate.

2′-O-Methyluridine is a natural product that found in RNA such as rRNA, snRNA, snoRNA and tRNA in Archaea, Bacteria, and Eukaryota.

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker. This compound is used in the synthesis of PROTACs.

Quercetin 3-O-Glc-(1→2)-Rha-7-O-Rha is a flavonol glycoside with no significant inhibitory effects on lipid accumulation induced by albumin oleate.

Hederagenin 28-O-{β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester}3-O-{α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl} is a saponin known for its antitumor and anti-inflammatory properties [1].

Isosaponarin 2''-O-glucoside (Isovitexin-2''-4'-di-O-beta-D-glucoside) is a natural product for research related to life sciences. The catalog number is TN6403 and the CAS number is 63316-27-8.

1-(3',5'-dimethoxy)phenyl-2-[4''-O-β-D-glucopyranosyl (6→1)-O-α-L-rhamnopyranosyl]phenylethane showed cytotoxic activities to Hela and hep2 cell lines.

Benzyl [5-O-benzoyl-β-D-apiofuranosyl(1→2)]-β-D-glucopyranoside is a natural product for research related to life sciences. The catalog number is TN5741 and the CAS number is 1097040-08-8.

Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside exhibits antioxidant activity.

3',5'-Di-O-acetyl-2'-deoxy-5,N3-dimethyl uridine is a Nucleoside Derivative - N-Alkylated nucleoside.

N6-Benzoyl-3’-O-(4,4’-dimethoxytrityl)-2’-O-   (2-methoxyethyl)adenosine is a useful organic compound for research related to life sciences and the catalog number is TNU1532.

3-Cyanovinyl-9-(5’-O-(4,4’-dimethoxytrityl)-2’-deoxyribofuranosyl)carbazole (trans: CAS#1044273-26-8) is a useful organic compound for research related to life sciences and the catalog number is TNU0955.

5'-O-Triphenylmethyl-2'-deoxyuridine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.

N6-Benzoyl-3'-O-(2-methoxyethyl)adenosine is a Nucleoside Derivative - 3'-Modified nucleoside.

N1-Ethyl-2’-O-TBDMS-5’-O-DMTr-3’-phosphoramidite (catalog number TNU1141) is a valuable organic compound used in life sciences research.

Phosphorodithioic acid, S-(2-butylthioethyl) O,O-diethyl ester is a bioactive chemical.