Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Apoptosis
    (1)
  • Autophagy
    (1)
  • JAK
    (3)
  • Others
    (1)
Filter
Search Result
Results for "

cyt387

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4
    TargetMol | Activity
Momelotinib
CYT11387,CYT387,LM-1149
T18491056634-68-4
Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhibition of JAK1/2 activation, inhibition of the JAK-STAT signaling pathway, and so the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
TargetMol | Citations Cited
Momelotinib sulfate
CYT387 sulfate salt
T150381056636-06-6
Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.
  • Inquiry Price
7-10 days
Size
QTY
Momelotinib Mesylate
CYT387 (Mesylate)
T150371056636-07-7
Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.
  • Inquiry Price
1-2 weeks
Size
QTY
FC11409B
T708211380411-57-3
FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.
  • Inquiry Price
6-8 weeks
Size
QTY