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By Target- JAK
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Biochemicals
- Autophagy
- Cell Cycle/Checkpoint
- Cytoskeletal Signaling
- Chromatin/Epigenetic
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- ROS
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- Drug Metabolite
- Endogenous Metabolite
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- Fatty Acid Synthase
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- Glucosidase
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- HIF/HIF Prolyl-Hydroxylase
- HMG-CoA Reductase
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- IDO
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- Tumor
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- Alangiaceae
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- Hydrolases,EC 3
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Search Result
Results for "
cyt387 sulfate
" in TargetMol Product Catalog- Inhibitors & Agonists4
Momelotinib sulfate
T150381056636-06-6
Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.
- $46
Size
QTY
Momelotinib HCl
T708231380317-28-1
Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.
- $1,520
Size
QTY
Momelotinib
Cited
T18491056634-68-4
Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhibition of JAK1/2 activation, inhibition of the JAK-STAT signaling pathway, and so the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells.
- $32
Size
QTY
CitedMomelotinib Mesylate
T150371056636-07-7
Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.
- $1,520
Size
QTY
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