d591 hydrochloride

2’-Deoxy-2’-fluoro-β-D-arabinocytidine hydrochloride is a cytosine nucleoside analog with inhibitory effects on DNA methyltransferase , with potential antimetabolic and antitumor activity.

D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.

D-Carnitine hydrochloride ((S)-Carnitine Hydrochloride) is a constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.

D-methionine sulfoxide hydrochloride is the D-isomer of methionine sulfoxide hydrochloride. Methionine sulfoxide is the oxidation product of methionine. Methionine is a restrictive amino acid in milk or legume proteins and is easily oxidized during storag

Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.

1,4-Dideoxy-1,4-imino-D-arabinitol (DAB) functions as an inhibitor of glycogen phosphorylase, a crucial enzyme in glycogenolysis, demonstrating the ability to hinder this process in isolated liver cells (IC50= 1.0 µM) and cerebral cortex and cerebellum homogenates (IC50s = 463 and 383 nM, respectively). Employed extensively in different animal models, DAB inhibits glycogenolysis within the liver and brain.

D-Ala-Lys-AMCA hydrochloride is a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1) that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into Caco-2 cells and liver cancer cells.

D-Alanine ethyl ester hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66104 and the CAS number is 6331-09-5.

D-Leucine methyl ester hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66885 and the CAS number is 5845-53-4.

N(G)-Nitro-D-arginine methyl ester (D-NAME) is the less active enantiomer of the nitric oxide (NO) synthase inhibitor N(G)-nitro-L-arginine methyl ester . D-NAME was initially thought to be inactive and was often used as a negative control for L-NAME. Later studies showed that D-NAME (40 mg/kg/day in rats) can have similar but less pronounced effects as L-NAME (40 mg/kg/day in rats) in the cardiovascular system, particularly at long-term timepoints. D-NAME (3-10 µg/mouse) had no effect on nociception in mice assessed using the tail flick test.

cis-4-Hydroxy-D-proline hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66933 and the CAS number is 77449-94-6.

(+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP . (+)-D-threo-PDMP is an inhibitor of glucosylceramide synthase. It inhibits glucosylceramide synthase by 50% when used at a concentration of 5 μM in an enzyme assay. (+)-D-threo-PDMP is the active component of racemic DL-threo-PDMP .

D(+)-Galactosamine hydrochloride (D-Galactosamine HCl) hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice.

3-Azido-D-alanine hydrochloride, an azido-modified derivative of D-alanine hydrochloride, serves as a reagent in click chemistry labeling research [1].

2-Amino-6-(propylamino)-5,6-dihydrobenzo[d]thiazol-7(4H)-one hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64682.

tans-4-Hydroxy-D-proline methyl ester hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65562 and the CAS number is 481704-21-6.

D-erythro-Sphingosine hydrochloride, also known as Erythrosphingosine, serves as a specific TRPM3 activator and induces retinoblastoma protein dephosphorylation.

D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor.1,2It is the active enanantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP . In MDCK kidney epithelial cells, D-threo-PPMP induces a 70% reduction in cell growthin vitroat 20 μM and significantly inhibits DNA synthesis at 3 μM.3[Matreya, LLC. Catalog No. 1865] 1.Shen, W., Henry, A.G., Paumier, K.L., et al.Inhibition of glucosylceramide synthase stimulates autophagy flux in neuronsJ. Neurochem.129(5)884-894(2014) 2.Lee, L., Abe, A., and Shayman, J.A.Improved inhibitors of glucosylceramide synthaseJ. Biol. Chem.274(21)14662-14669(1999) 3.Abe, A., Inokuchi, J.-i., Jimbo, M., et al.Improved inhibitors of glucosylceramide synthaseJ. Biochem.111(2)191-196(1992)

D-Homophenylalanine ethyl ester hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66011 and the CAS number is 90940-54-8.

D-Cl-amidine hydrochloride is a potent and highly selective inhibitor of PAD1. It exhibits excellent tolerance and does not induce significant toxicity [1].

D-Ornithine monohydrochloride is an endogenous metabolite that regulates intramuscular hormone levels, and has been used in studies of dry skin and insomnia.3,5-Dihydroxybenzoic acid is an endogenous metabolite that regulates intramuscular hormone levels.

D-2-Aminoglutarimide is a synthetic intermediate.1It has been used in the synthesis of hydantoins with anti-angiogenic and cancer cell differentiation-inducing activities. 1.Yamaguchi, J., Noguchi-Yachide, T., Sakaguchi, Y., et al.Synthesis of new hydantoins bearing glutarimide or succinimide moiety and their evaluation for cell differentiation-inducing and anti-angiogenic activitiesHeterocycles91(4)764-781(2015)

4,5,6,7-Tetrahydro-1H-benzo[d]imidazole-5-carboxylic acid hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66049 and the CAS number is 131020-57-0.

N2-Fmoc-D-lysine Hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65188 and the CAS number is 201002-47-3.

tans-4-Hydroxy-D-proline hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65471 and the CAS number is 142347-81-7.

D-Mabuterol hydrochloride is a D isoform of Mabuterol, which is a selective β2 adrenoreceptor agonist. Mabuterol has been found to decrease the blood pressure in rats and increase heart rate and contractile force in guinea pigs. Mabuterol inhibited the positive inotropic effect of isoprenaline but has no effect on alpha-adrenergic, acetylcholine and histamine receptors.

H-D-Aha-OH (hydrochloride), a click chemistry reagent, contains an azide group.

Bz-D-Arg-pNA hydrochloride is a competitive trypsin inhibitor.

1-Amino-1-deoxy-D-fructose is an amino monosaccharide.1It induces site-specific DNA damage at pyrimidine residues in cell-free assays. 1-Amino-1-deoxy-D-fructose moieties have been found as a component of fructosamines, glycated serum proteins that are elevated in patients with conditions such as diabetes.2,3

D,L-erythro-PDMP hydrochloride, an erythro isomer of PDMP, inhibits the growth of cultured rabbit skin fibroblasts and serves as an effective inhibitor of UDP-glucose:ceramide glucosyltransferase.

3-(Piperidin-4-yl)benzo[d]oxazol-2(3H)-one hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66383 and the CAS number is 162045-54-7.

H-D-Phe-Pip-Arg-pNA hydrochloride, a chromogenic substrate, mimics the N-terminal segment of the A alpha chain of fibrinogen, the native substrate of thrombin. It displays specificity towards thrombin and is employed for quantifying antithrombin-heparin cofactor (AT-III). The utilization of H-D-Phe-Pip-Arg-pNA hydrochloride in the AT-III assay enables a sensitive, accurate, and straightforward measurement process.