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  • 5-HT Receptor
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Results for "da 6" in TargetMol Product Catalog
  • Inhibitor Products
    11
    TargetMol | Activity
Diethyl aminoethyl hexanoate citrate
T19280220439-24-7
Diethyl aminoethyl hexanoate citrate (2-Diethylaminoethyl hexanoate citrate) is a compound that is widely used as a plant growth regulator stimulates the regeneration of adventitious buds.
  • $41
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N6-Methyl-dA phosphoramidite
T38454105931-58-6
N6-Methyl-dA phosphoramidite can be used in the synthesis of oligodeoxyribonucleotides.
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7-10 days
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5'-O-DMT-N6-ibu-dA
T39332190834-10-7
5'-O-DMT-N6-ibu-dA can be used in the synthesis of oligodeoxyribonucleotides.
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    5'-O-DMT-N6-Me-2'-dA
    T4112698056-69-0
    5'-O-DMT-N6-Me-2'-dA is a nucleoside with protective and modification effects.
    • $30
    7-10 days
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    5’-O-DMTr-N6-Fmoc-dA-phosphoramidite
    TNU1227109420-86-2
    5'-O-DMTr-N6-Fmoc-dA-phosphoramidite is a Nucleoside Phosphoramidite.
    • Inquiry Price
    7-10 days
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    Niaprazine
    T3694927367-90-4
    Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low affinity for the vesicular monoamine transporter and for D2, α2, β, H1 and mAch receptors. Niaprazine, particularly the (+)stereoisomer, has a higher affinity for α1 (Ki = 77 nM) and 5-HT2 (Ki = 25 nM) binding sites, but is poorly recognized by 5-HT1A and 5-HT1B binding sites[2]. Niaprazine (60 mg/kg; i.p.; once) treatment increases rat brain 5-hydroxyindole acetic acid (5-HIAA) concentrations 30 min after treatment, and reduced them at 3-8 hr after treatment. Niaprazine also produces a short-lasting depletion of rat brain noradrenaline (NA) and dopamine (DA)[3]. Animal Model: Male Sprague-Dawley rats (150-200 g)[3] [1]. D Scherman, et al. Molecular pharmacology of niaprazine. Prog Neuropsychopharmacol Biol Psychiatry. 1988;12(6):989-1001. [2]. P G Rossi, et al. Niaprazine in the treatment of autistic disorder. J Child Neurol. 1999 Aug;14(8):547-50. [3]. P E Keane, et al. The effect of niaprazine on the turnover of 5-hydroxytryptamine in the rat brain. Neuropharmacology. 1982 Feb;21(2):163-9.
    • $40
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    Centanafadine hydrochloride
    T10758L923981-14-0
    Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).
    • $54
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    Centanafadine
    T10758924012-43-1
    Centanafadine is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).
    • $1,520
    1-2 weeks
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    Dasotraline
    T60607675126-05-3
    Dasotraline is a triple reuptake inhibitor that blocks dopamine(DA), norepinephrine(NE), and serotonin [5-hydroxytryptamine (5-HT)] transporters with IC 50 values of 4, 6, and 11 nM, respectively. Dasotraline represents a potential new class of antidepressant agents.
    • $2,140
    1-2 weeks
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    MAO-IN-M30 dihydrochloride
    T3803464821-19-8
    MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson's disease model.
    • $30
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    C-DIM12
    T3106178946-89-9
    C-DIM12 induced expression of Nurr1-regulated genes. C-DIM12 increased expression of transfected human Nurr1, induced Nurr1 protein expression in primary dopaminergic neurons and enhanced neuronal survival from exposure to 6-OHDA.
    • $39
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